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NSA2

GENERAL INFORMATION

Gene name

 NSA2

Gene description

 NSA2 ribosome biogenesis homolog

Protein class

 Plasma proteins
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA043487
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Tonsil

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NSA2 (HGNC Symbol)

Synonyms

 FLJ94393, HCLG1, HUSSY-29, TINP1

Description

 NSA2 ribosome biogenesis homolog (HGNC Symbol)

Entrez gene summary

 This gene encodes a nucleolar protein involved in cell cycle regulation and proliferation. This gene was identified based on sequence similarity to a highly conserved Saccharomyces cerevisiae gene encoding a pre-ribosomal protein, which is involved in large ribosomal subunit biogenesis. The encoded protein is found at elevated levels in diabetic nephropathy. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified. [provided by RefSeq, Nov 2012]

Chromosome

 5

Cytoband

 q13.3

Chromosome location (bp)

 74766991 - 74780113

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164346 (version 83.38)

Entrez gene

 10412

UniProt

 O95478 (UniProt - Evidence at protein level)

neXtProt

 NX_O95478

Antibodypedia

 NSA2 antibodies

PROTEIN BROWSER
NSA2-001
NSA2-003
NSA2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NSA2-001
ENSP00000483484
ENST00000610426
O95478 [Direct mapping]
Ribosome biogenesis protein NSA2 homolog
Q5J7U2 [Target identity:100%; Query identity:100%]
TGF beta-inducible nuclear protein 1; TGF-beta inducible nuclear protein; cDNA, FLJ94393, Homo sapiens TGF beta-inducible nuclear protein 1 (TINP1), mRNA
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Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0006364 [rRNA processing]
GO:0030529 [ribonucleoprotein complex]
GO:0044822 [poly(A) RNA binding]
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 260 aa
30.1 kDa 		No 0
NSA2-003
ENSP00000427266
ENST00000515524
H0YAI9 [Direct mapping]
Ribosome biogenesis protein NSA2 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 98 aa
11.4 kDa 		No 0
NSA2-201
ENSP00000296802
ENST00000296802
A0A0A0MQZ6 [Direct mapping]
Ribosome biogenesis protein NSA2 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 189 aa
22.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.