Expression of SEPT8 in cancer - Summary - The Human Protein Atlas

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SEPT8

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Septin 8

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA005665

GENE INFORMATION
Gene name	SEPT8 (HGNC Symbol)
Synonyms	KIAA0202, SEP2
Description	Septin 8 (HGNC Symbol)
Entrez gene summary	This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Chromosome	5
Cytoband	q31.1
Chromosome location (bp)	132750817 - 132807241
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164402 (version 83.38)
Entrez gene	23176
UniProt	Q92599 (UniProt - Evidence at protein level)
neXtProt	NX_Q92599
Antibodypedia	SEPT8 antibodies

PROTEIN BROWSER

SEPT8-001	SEPT8-002	SEPT8-003	SEPT8-004	SEPT8-005	SEPT8-006	SEPT8-007	SEPT8-012	SEPT8-013	SEPT8-016	SEPT8-201	SEPT8-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SEPT8-001 ENSP00000367971 ENST00000378699	Q92599 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] Show all	369 aa 43.5 kDa	No	0
SEPT8-002 ENSP00000367991 ENST00000378719	Q92599 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] GO:0043209 [myelin sheath] Show all	483 aa 55.8 kDa	No	0
SEPT8-003 ENSP00000296873 ENST00000296873	Q92599 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] Show all	429 aa 49.8 kDa	No	0
SEPT8-004 ENSP00000367978 ENST00000378706	A6NMH6 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	430 aa 49.9 kDa	No	0
SEPT8-005 ENSP00000367973 ENST00000378701	A6NFQ9 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	440 aa 50.9 kDa	No	0
SEPT8-006 ENSP00000367993 ENST00000378721	F8W8I8 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	460 aa 53.2 kDa	No	0
SEPT8-007 ENSP00000394766 ENST00000458488	Q92599 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] Show all	442 aa 51.2 kDa	No	0
SEPT8-012 ENSP00000411823 ENST00000414594	C9J4G8 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	97 aa 11.6 kDa	No	0
SEPT8-013 ENSP00000407421 ENST00000453480	C9JV02 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	130 aa 15 kDa	No	0
SEPT8-016 ENSP00000360548 ENST00000371493	A0A0A0MRP8 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	79 aa 9.3 kDa	No	0
SEPT8-201 ENSP00000399840 ENST00000448933	Q92599 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] Show all	369 aa 43.5 kDa	No	0
SEPT8-202 ENSP00000483876 ENST00000620483	A0A087X142 [Direct mapping] Septin-8 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	426 aa 49.4 kDa	No	0

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The Human Protein Atlas

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