Fields »
ABOUT
HELP
BLOG
RPS14

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 RPS14

Gene description

 Ribosomal protein S14

Protein class

 Plasma proteins
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the cytosol & endoplasmic reticulum.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Endoplasmic reticulum (validated), Cytosol (validated)

DATA RELIABILITY

Reliability score

 Validated based on 1 antibody.
HPA018504
SHOW MORE

ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the cytosol & endoplasmic reticulum.

Main location

 Endoplasmic reticulum (validated), Cytosol (validated)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA018504 A-431 Endoplasmic reticulum
Cytosol
HPA018504 U-2 OS Endoplasmic reticulum
Cytosol
HPA018504 U-251 MG Endoplasmic reticulum
Cytosol

GENE INFORMATION

Gene name

 RPS14 (HGNC Symbol)

Synonyms

 EMTB, S14

Description

 Ribosomal protein S14 (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 q33.1

Chromosome location (bp)

 150443190 - 150449756

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164587 (version 83.38)

Entrez gene

 6208

UniProt

 P62263 (UniProt - Evidence at protein level)

neXtProt

 NX_P62263

Antibodypedia

 RPS14 antibodies

PROTEIN BROWSER
RPS14-001
RPS14-005
RPS14-006
RPS14-007
RPS14-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPS14-001
ENSP00000385958
ENST00000401695
P62263 [Direct mapping]
40S ribosomal protein S14
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000028 [ribosomal small subunit assembly]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006417 [regulation of translation]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022627 [cytosolic small ribosomal subunit]
GO:0030218 [erythrocyte differentiation]
GO:0030490 [maturation of SSU-rRNA]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0045182 [translation regulator activity]
GO:0048027 [mRNA 5'-UTR binding]
GO:0070062 [extracellular exosome]
GO:0070181 [small ribosomal subunit rRNA binding]
Show all
 151 aa
16.3 kDa 		No 0
RPS14-005
ENSP00000311028
ENST00000312037
P62263 [Direct mapping]
40S ribosomal protein S14
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000028 [ribosomal small subunit assembly]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006417 [regulation of translation]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022627 [cytosolic small ribosomal subunit]
GO:0030218 [erythrocyte differentiation]
GO:0030490 [maturation of SSU-rRNA]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0045182 [translation regulator activity]
GO:0048027 [mRNA 5'-UTR binding]
GO:0070062 [extracellular exosome]
GO:0070181 [small ribosomal subunit rRNA binding]
Show all
 151 aa
16.3 kDa 		No 0
RPS14-006
ENSP00000428509
ENST00000521466
P62263 [Direct mapping]
40S ribosomal protein S14
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000028 [ribosomal small subunit assembly]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006417 [regulation of translation]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022627 [cytosolic small ribosomal subunit]
GO:0030218 [erythrocyte differentiation]
GO:0030490 [maturation of SSU-rRNA]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0045182 [translation regulator activity]
GO:0048027 [mRNA 5'-UTR binding]
GO:0070062 [extracellular exosome]
GO:0070181 [small ribosomal subunit rRNA binding]
Show all
 151 aa
16.3 kDa 		No 0
RPS14-007
ENSP00000428536
ENST00000519855
H0YB22 [Direct mapping]
40S ribosomal protein S14
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
 120 aa
12.8 kDa 		No 0
RPS14-201
ENSP00000385425
ENST00000407193
P62263 [Direct mapping]
40S ribosomal protein S14
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000028 [ribosomal small subunit assembly]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006417 [regulation of translation]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022627 [cytosolic small ribosomal subunit]
GO:0030218 [erythrocyte differentiation]
GO:0030490 [maturation of SSU-rRNA]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0045182 [translation regulator activity]
GO:0048027 [mRNA 5'-UTR binding]
GO:0070062 [extracellular exosome]
GO:0070181 [small ribosomal subunit rRNA binding]
Show all
 151 aa
16.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.