Cell atlas - BMPER - The Human Protein Atlas

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BMPER

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	BMPER
Gene description	BMP binding endothelial regulator
Protein class	Disease related genes Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (U-138 MG, HBF TERT88, BJ)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-138 MG, HBF TERT88, BJ) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	BMPER (HGNC Symbol)
Synonyms	CRIM3, Cv2
Description	BMP binding endothelial regulator (HGNC Symbol)
Entrez gene summary	This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011]
Chromosome	7
Cytoband	p14.3
Chromosome location (bp)	33904911 - 34155872
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164619 (version 83.38)
Entrez gene	168667
UniProt	Q8N8U9 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N8U9
Antibodypedia	BMPER antibodies

PROTEIN BROWSER

BMPER-001	BMPER-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BMPER-001 ENSP00000297161 ENST00000297161	Q8N8U9 [Direct mapping] BMP-binding endothelial regulator protein A0A090N7U6 [Target identity:100%; Query identity:100%] BMP-binding endothelial regulator protein Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Plasma proteins Disease related genes Show all	GO:0001657 [ureteric bud development] GO:0002043 [blood vessel endothelial cell proliferation involved in sprouting angiogenesis] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0010594 [regulation of endothelial cell migration] GO:0030514 [negative regulation of BMP signaling pathway] GO:0042118 [endothelial cell activation] GO:0048839 [inner ear development] GO:0060393 [regulation of pathway-restricted SMAD protein phosphorylation] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] Show all	685 aa 76 kDa	Yes	0
BMPER-004 ENSP00000399843 ENST00000436222	C9JY72 [Direct mapping] BMP-binding endothelial regulator protein Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		161 aa 17.3 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.