Tissue expression of SLC29A4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	SLC29A4
Gene description	Solute carrier family 29 (equilibrative nucleoside transporter), member 4
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (adipose tissue)
GTEx:	Mixed
FANTOM5:	Tissue enhanced (retina)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (adipose tissue)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (retina)

GENE INFORMATION
Gene name	SLC29A4 (HGNC Symbol)
Synonyms	ENT4, FLJ34923
Description	Solute carrier family 29 (equilibrative nucleoside transporter), member 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the SLC29A/ENT transporter protein family. The encoded membrane protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Chromosome	7
Cytoband	p22.1
Chromosome location (bp)	5274369 - 5306870
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164638 (version 83.38)
Entrez gene	222962
UniProt	Q7RTT9 (UniProt - Evidence at protein level)
neXtProt	NX_Q7RTT9
Antibodypedia	SLC29A4 antibodies

PROTEIN BROWSER

SLC29A4-001	SLC29A4-002	SLC29A4-003	SLC29A4-004	SLC29A4-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC29A4-001 ENSP00000380081 ENST00000396872	Q7RTT9 [Direct mapping] Equilibrative nucleoside transporter 4 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005337 [nucleoside transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0008504 [monoamine transmembrane transporter activity] GO:0015844 [monoamine transport] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] GO:0055085 [transmembrane transport] GO:1901642 [nucleoside transmembrane transport] Show all	530 aa 58.1 kDa	No	>9
SLC29A4-002 ENSP00000297195 ENST00000297195	Q7RTT9 [Direct mapping] Equilibrative nucleoside transporter 4 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005337 [nucleoside transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] GO:0055085 [transmembrane transport] GO:1901642 [nucleoside transmembrane transport] Show all	530 aa 58.1 kDa	No	>9
SLC29A4-003 ENSP00000385845 ENST00000406453	Q7RTT9 [Direct mapping] Equilibrative nucleoside transporter 4 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005337 [nucleoside transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] GO:0055085 [transmembrane transport] GO:1901642 [nucleoside transmembrane transport] Show all	516 aa 56.4 kDa	No	>9
SLC29A4-004 ENSP00000406803 ENST00000434816	C9IYM7 [Direct mapping] Equilibrative nucleoside transporter 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0005337 [nucleoside transmembrane transporter activity] GO:0008504 [monoamine transmembrane transporter activity] GO:0015844 [monoamine transport] GO:0016021 [integral component of membrane] GO:1901642 [nucleoside transmembrane transport] Show all	163 aa 17.9 kDa	No	3
SLC29A4-005 ENSP00000413271 ENST00000444741	C9JZA2 [Direct mapping] Equilibrative nucleoside transporter 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005337 [nucleoside transmembrane transporter activity] GO:0008504 [monoamine transmembrane transporter activity] GO:0015844 [monoamine transport] GO:0016021 [integral component of membrane] GO:1901642 [nucleoside transmembrane transport] Show all	151 aa 16.2 kDa	No	2