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GPER1

CANCER ATLAS

Gene description

 G protein-coupled estrogen receptor 1

Protein class

 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA027052

GENE INFORMATION

Gene name

 GPER1 (HGNC Symbol)

Synonyms

 CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR

Description

 G protein-coupled estrogen receptor 1 (HGNC Symbol)

Entrez gene summary

 This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

 7

Cytoband

 p22.3

Chromosome location (bp)

 1082208 - 1093815

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164850 (version 83.38)

Entrez gene

 2852

UniProt

 Q99527 (UniProt - Evidence at protein level)

neXtProt

 NX_Q99527

Antibodypedia

 GPER1 antibodies

PROTEIN BROWSER
GPER1-030
GPER1-031
GPER1-032
GPER1-033
GPER1-201
GPER1-202
GPER1-203

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GPER1-030
ENSP00000297469
ENST00000297469
Q99527 [Direct mapping]
G-protein coupled estrogen receptor 1
A0A024R849 [Target identity:100%; Query identity:100%]
G protein-coupled receptor 30, isoform CRA_a
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0000139 [Golgi membrane]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0001956 [positive regulation of neurotransmitter secretion]
GO:0002695 [negative regulation of leukocyte activation]
GO:0003682 [chromatin binding]
GO:0004930 [G-protein coupled receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006954 [inflammatory response]
GO:0007049 [cell cycle]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0008284 [positive regulation of cell proliferation]
GO:0008285 [negative regulation of cell proliferation]
GO:0010579 [positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0014068 [positive regulation of phosphatidylinositol 3-kinase signaling]
GO:0014069 [postsynaptic density]
GO:0016021 [integral component of membrane]
GO:0017082 [mineralocorticoid receptor activity]
GO:0019228 [neuronal action potential]
GO:0030054 [cell junction]
GO:0030263 [apoptotic chromosome condensation]
GO:0030264 [nuclear fragmentation involved in apoptotic nuclear change]
GO:0030284 [estrogen receptor activity]
GO:0030335 [positive regulation of cell migration]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030518 [intracellular steroid hormone receptor signaling pathway]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030819 [positive regulation of cAMP biosynthetic process]
GO:0031959 [mineralocorticoid receptor signaling pathway]
GO:0031966 [mitochondrial membrane]
GO:0032024 [positive regulation of insulin secretion]
GO:0032591 [dendritic spine membrane]
GO:0032962 [positive regulation of inositol trisphosphate biosynthetic process]
GO:0042734 [presynaptic membrane]
GO:0043065 [positive regulation of apoptotic process]
GO:0043198 [dendritic shaft]
GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043410 [positive regulation of MAPK cascade]
GO:0043679 [axon terminus]
GO:0044327 [dendritic spine head]
GO:0045087 [innate immune response]
GO:0045095 [keratin filament]
GO:0045599 [negative regulation of fat cell differentiation]
GO:0045742 [positive regulation of epidermal growth factor receptor signaling pathway]
GO:0045745 [positive regulation of G-protein coupled receptor protein signaling pathway]
GO:0045909 [positive regulation of vasodilation]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048786 [presynaptic active zone]
GO:0050728 [negative regulation of inflammatory response]
GO:0050769 [positive regulation of neurogenesis]
GO:0051053 [negative regulation of DNA metabolic process]
GO:0051055 [negative regulation of lipid biosynthetic process]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0055037 [recycling endosome]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070474 [positive regulation of uterine smooth muscle contraction]
GO:0071157 [negative regulation of cell cycle arrest]
GO:0071333 [cellular response to glucose stimulus]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0071375 [cellular response to peptide hormone stimulus]
GO:0071389 [cellular response to mineralocorticoid stimulus]
GO:0071392 [cellular response to estradiol stimulus]
GO:0090004 [positive regulation of establishment of protein localization to plasma membrane]
GO:0090200 [positive regulation of release of cytochrome c from mitochondria]
GO:0097481 [neuronal postsynaptic density]
GO:2000353 [positive regulation of endothelial cell apoptotic process]
GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway]
Show all
 375 aa
42.2 kDa 		No 7
GPER1-031
ENSP00000380277
ENST00000397088
Q99527 [Direct mapping]
G-protein coupled estrogen receptor 1
A0A024R849 [Target identity:100%; Query identity:100%]
G protein-coupled receptor 30, isoform CRA_a
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0000139 [Golgi membrane]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0001956 [positive regulation of neurotransmitter secretion]
GO:0002695 [negative regulation of leukocyte activation]
GO:0003682 [chromatin binding]
GO:0004930 [G-protein coupled receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006954 [inflammatory response]
GO:0007049 [cell cycle]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0008284 [positive regulation of cell proliferation]
GO:0008285 [negative regulation of cell proliferation]
GO:0010579 [positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0014068 [positive regulation of phosphatidylinositol 3-kinase signaling]
GO:0014069 [postsynaptic density]
GO:0016021 [integral component of membrane]
GO:0017082 [mineralocorticoid receptor activity]
GO:0019228 [neuronal action potential]
GO:0030054 [cell junction]
GO:0030263 [apoptotic chromosome condensation]
GO:0030264 [nuclear fragmentation involved in apoptotic nuclear change]
GO:0030284 [estrogen receptor activity]
GO:0030335 [positive regulation of cell migration]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030518 [intracellular steroid hormone receptor signaling pathway]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030819 [positive regulation of cAMP biosynthetic process]
GO:0031959 [mineralocorticoid receptor signaling pathway]
GO:0031966 [mitochondrial membrane]
GO:0032024 [positive regulation of insulin secretion]
GO:0032591 [dendritic spine membrane]
GO:0032962 [positive regulation of inositol trisphosphate biosynthetic process]
GO:0042734 [presynaptic membrane]
GO:0043065 [positive regulation of apoptotic process]
GO:0043198 [dendritic shaft]
GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043410 [positive regulation of MAPK cascade]
GO:0043679 [axon terminus]
GO:0044327 [dendritic spine head]
GO:0045087 [innate immune response]
GO:0045095 [keratin filament]
GO:0045599 [negative regulation of fat cell differentiation]
GO:0045742 [positive regulation of epidermal growth factor receptor signaling pathway]
GO:0045745 [positive regulation of G-protein coupled receptor protein signaling pathway]
GO:0045909 [positive regulation of vasodilation]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048786 [presynaptic active zone]
GO:0050728 [negative regulation of inflammatory response]
GO:0050769 [positive regulation of neurogenesis]
GO:0051053 [negative regulation of DNA metabolic process]
GO:0051055 [negative regulation of lipid biosynthetic process]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0055037 [recycling endosome]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070474 [positive regulation of uterine smooth muscle contraction]
GO:0071157 [negative regulation of cell cycle arrest]
GO:0071333 [cellular response to glucose stimulus]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0071375 [cellular response to peptide hormone stimulus]
GO:0071389 [cellular response to mineralocorticoid stimulus]
GO:0071392 [cellular response to estradiol stimulus]
GO:0090004 [positive regulation of establishment of protein localization to plasma membrane]
GO:0090200 [positive regulation of release of cytochrome c from mitochondria]
GO:0097481 [neuronal postsynaptic density]
GO:2000353 [positive regulation of endothelial cell apoptotic process]
GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway]
Show all
 375 aa
42.2 kDa 		No 7
GPER1-032
ENSP00000385151
ENST00000401670
Q99527 [Direct mapping]
G-protein coupled estrogen receptor 1
A0A024R849 [Target identity:100%; Query identity:100%]
G protein-coupled receptor 30, isoform CRA_a
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0000139 [Golgi membrane]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0001956 [positive regulation of neurotransmitter secretion]
GO:0002695 [negative regulation of leukocyte activation]
GO:0003682 [chromatin binding]
GO:0004930 [G-protein coupled receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006954 [inflammatory response]
GO:0007049 [cell cycle]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0008284 [positive regulation of cell proliferation]
GO:0008285 [negative regulation of cell proliferation]
GO:0010579 [positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0014068 [positive regulation of phosphatidylinositol 3-kinase signaling]
GO:0014069 [postsynaptic density]
GO:0016021 [integral component of membrane]
GO:0017082 [mineralocorticoid receptor activity]
GO:0019228 [neuronal action potential]
GO:0030054 [cell junction]
GO:0030263 [apoptotic chromosome condensation]
GO:0030264 [nuclear fragmentation involved in apoptotic nuclear change]
GO:0030284 [estrogen receptor activity]
GO:0030335 [positive regulation of cell migration]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030518 [intracellular steroid hormone receptor signaling pathway]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030819 [positive regulation of cAMP biosynthetic process]
GO:0031959 [mineralocorticoid receptor signaling pathway]
GO:0031966 [mitochondrial membrane]
GO:0032024 [positive regulation of insulin secretion]
GO:0032591 [dendritic spine membrane]
GO:0032962 [positive regulation of inositol trisphosphate biosynthetic process]
GO:0042734 [presynaptic membrane]
GO:0043065 [positive regulation of apoptotic process]
GO:0043198 [dendritic shaft]
GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043410 [positive regulation of MAPK cascade]
GO:0043679 [axon terminus]
GO:0044327 [dendritic spine head]
GO:0045087 [innate immune response]
GO:0045095 [keratin filament]
GO:0045599 [negative regulation of fat cell differentiation]
GO:0045742 [positive regulation of epidermal growth factor receptor signaling pathway]
GO:0045745 [positive regulation of G-protein coupled receptor protein signaling pathway]
GO:0045909 [positive regulation of vasodilation]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048786 [presynaptic active zone]
GO:0050728 [negative regulation of inflammatory response]
GO:0050769 [positive regulation of neurogenesis]
GO:0051053 [negative regulation of DNA metabolic process]
GO:0051055 [negative regulation of lipid biosynthetic process]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0055037 [recycling endosome]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070474 [positive regulation of uterine smooth muscle contraction]
GO:0071157 [negative regulation of cell cycle arrest]
GO:0071333 [cellular response to glucose stimulus]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0071375 [cellular response to peptide hormone stimulus]
GO:0071389 [cellular response to mineralocorticoid stimulus]
GO:0071392 [cellular response to estradiol stimulus]
GO:0090004 [positive regulation of establishment of protein localization to plasma membrane]
GO:0090200 [positive regulation of release of cytochrome c from mitochondria]
GO:0097481 [neuronal postsynaptic density]
GO:2000353 [positive regulation of endothelial cell apoptotic process]
GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway]
Show all
 375 aa
42.2 kDa 		No 7
GPER1-033
ENSP00000410487
ENST00000413368
C9J3W2 [Direct mapping]
G-protein-coupled estrogen receptor 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0016021 [integral component of membrane]
Show all
 73 aa
7.7 kDa 		No 1
GPER1-201
ENSP00000380281
ENST00000397092
Q99527 [Direct mapping]
G-protein coupled estrogen receptor 1
A0A024R849 [Target identity:100%; Query identity:100%]
G protein-coupled receptor 30, isoform CRA_a
Show all
G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0000139 [Golgi membrane]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0001956 [positive regulation of neurotransmitter secretion]
GO:0002695 [negative regulation of leukocyte activation]
GO:0003682 [chromatin binding]
GO:0003707 [steroid hormone receptor activity]
GO:0004930 [G-protein coupled receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006954 [inflammatory response]
GO:0007049 [cell cycle]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0008144 [drug binding]
GO:0008284 [positive regulation of cell proliferation]
GO:0008285 [negative regulation of cell proliferation]
GO:0010579 [positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0014068 [positive regulation of phosphatidylinositol 3-kinase signaling]
GO:0014069 [postsynaptic density]
GO:0016021 [integral component of membrane]
GO:0017082 [mineralocorticoid receptor activity]
GO:0019228 [neuronal action potential]
GO:0030054 [cell junction]
GO:0030263 [apoptotic chromosome condensation]
GO:0030264 [nuclear fragmentation involved in apoptotic nuclear change]
GO:0030284 [estrogen receptor activity]
GO:0030335 [positive regulation of cell migration]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030518 [intracellular steroid hormone receptor signaling pathway]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030819 [positive regulation of cAMP biosynthetic process]
GO:0031959 [mineralocorticoid receptor signaling pathway]
GO:0031966 [mitochondrial membrane]
GO:0032024 [positive regulation of insulin secretion]
GO:0032591 [dendritic spine membrane]
GO:0032962 [positive regulation of inositol trisphosphate biosynthetic process]
GO:0042562 [hormone binding]
GO:0042734 [presynaptic membrane]
GO:0043065 [positive regulation of apoptotic process]
GO:0043198 [dendritic shaft]
GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043410 [positive regulation of MAPK cascade]
GO:0043679 [axon terminus]
GO:0044327 [dendritic spine head]
GO:0045087 [innate immune response]
GO:0045095 [keratin filament]
GO:0045599 [negative regulation of fat cell differentiation]
GO:0045742 [positive regulation of epidermal growth factor receptor signaling pathway]
GO:0045745 [positive regulation of G-protein coupled receptor protein signaling pathway]
GO:0045909 [positive regulation of vasodilation]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048786 [presynaptic active zone]
GO:0050728 [negative regulation of inflammatory response]
GO:0050769 [positive regulation of neurogenesis]
GO:0051053 [negative regulation of DNA metabolic process]
GO:0051055 [negative regulation of lipid biosynthetic process]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0055037 [recycling endosome]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070474 [positive regulation of uterine smooth muscle contraction]
GO:0071157 [negative regulation of cell cycle arrest]
GO:0071333 [cellular response to glucose stimulus]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0071375 [cellular response to peptide hormone stimulus]
GO:0071389 [cellular response to mineralocorticoid stimulus]
GO:0071392 [cellular response to estradiol stimulus]
GO:0090004 [positive regulation of establishment of protein localization to plasma membrane]
GO:0090200 [positive regulation of release of cytochrome c from mitochondria]
GO:0097481 [neuronal postsynaptic density]
GO:2000353 [positive regulation of endothelial cell apoptotic process]
GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway]
Show all
 375 aa
42.2 kDa 		No 7
GPER1-202
ENSP00000479553
ENST00000617001
A0A087WVN0 [Direct mapping]
G-protein-coupled estrogen receptor 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Show all
GO:0004930 [G-protein coupled receptor activity]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0016021 [integral component of membrane]
Show all
 408 aa
45.5 kDa 		No 6
GPER1-203
ENSP00000483756
ENST00000619052
A0A087X0Z4 [Direct mapping]
G-protein-coupled estrogen receptor 1
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
 176 aa
19 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.