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Basal cell carcinomas of skin and urothelial cancers exhibited moderate to strong cytoplasmic immunoreactivity while several cases of prostate cancers displayed moderate staining. Remaining malignant tissues were generally negative.
The majority of malignant cells displayed weak cytoplasmic staining or were negative. Occasional cases of hepatocellular carcinomas exhibited moderate cytoplasmic staining.
GENE INFORMATION
Gene name
SVEP1 (HGNC Symbol)
Synonyms
bA427L11.3, C9orf13, FLJ13529, POLYDOM
Description
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (HGNC Symbol)
Q4LDE5 [Direct mapping] Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1
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Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)