Cell atlas - WBSCR27 - The Human Protein Atlas

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WBSCR27

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Focal adhesion sites

Human cell
	Actin Filaments

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GENERAL INFORMATION
Gene name	WBSCR27
Gene description	Williams Beuren syndrome chromosome region 27
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the focal adhesion sites.
RNA cell category	Cell line enhanced (RPMI-8226, T-47d)
Protein evidence	Evidence at protein level
Main location	Localized to the Focal adhesion sites (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA022420
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RPMI-8226, T-47d) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the focal adhesion sites.

Main location

Focal adhesion sites (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA022420	A-431	Focal adhesion sites
	HPA022420	U-2 OS	No staining
	HPA022420	U-251 MG	Focal adhesion sites

GENE INFORMATION
Gene name	WBSCR27
Synonyms
Description	Williams Beuren syndrome chromosome region 27 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein belonging to ubiE/COQ5 methyltransferase family. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.22-q11.23. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q11.23
Chromosome location (bp)	73834590 - 73842535
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165171 (version 83.38)
Entrez gene	155368
UniProt	Q8N6F8 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N6F8
Antibodypedia	WBSCR27 antibodies

PROTEIN BROWSER

WBSCR27-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
WBSCR27-001 ENSP00000297873 ENST00000297873	Q8N6F8 [Direct mapping] Williams-Beuren syndrome chromosomal region 27 protein Show all	Predicted intracellular proteins Disease related genes Show all	GO:0005515 [protein binding] GO:0008757 [S-adenosylmethionine-dependent methyltransferase activity] GO:0032259 [methylation] Show all	245 aa 26.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.