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A majority of cancer cells displayed moderate cytoplasmic staining. Thyroid cancers and a majority of endometrial cancers were strongly stained. Most gliomas as well as several testicular cancers were weakly stained or negative.
GENE INFORMATION
Gene name
FBXO33 (HGNC Symbol)
Synonyms
Fbx33
Description
F-box protein 33 (HGNC Symbol)
Entrez gene summary
This locus represents an member of the F-box gene family. The encoded protein contains an F-box motif and a domain that might form a structure similar to a leucine-rich repeat found in placental RNAse inhibitor. This locus may be associated with copy number variation of UGT2B17 (GeneID 7367), which has been associated with susceptibility to osteoporosis.[provided by RefSeq, Sep 2010]