Cell atlas - C10orf10 - The Human Protein Atlas

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C10orf10

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus
	Vesicles

Human cell
	Nucleoplasm
	Vesicles

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GENERAL INFORMATION
Gene name	C10orf10
Gene description	Chromosome 10 open reading frame 10
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to vesicles. In addition localized to the nucleus.
RNA cell category	Cell line enhanced (HUVEC TERT2, HDLM-2, ASC TERT1)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved)
Additional location	In addition localized to the Nucleus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA037819
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HUVEC TERT2, HDLM-2, ASC TERT1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to vesicles. In addition localized to the nucleus.

Main location

Vesicles (approved)

Additional location

Nucleus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA037819	A-431	Nucleoplasm
	HPA037819	A-431	Vesicles
	HPA037819	Hep G2	Vesicles
	HPA037819	U-2 OS	Nucleus
	HPA037819	U-2 OS	Vesicles

GENE INFORMATION
Gene name	C10orf10 (HGNC Symbol)
Synonyms	DEPP, FIG, Fseg
Description	Chromosome 10 open reading frame 10 (HGNC Symbol)
Entrez gene summary	The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and activation of the transcription factor ELK1. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q11.21
Chromosome location (bp)	44970981 - 44978810
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165507 (version 83.38)
Entrez gene	11067
UniProt	Q9NTK1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NTK1
Antibodypedia	C10orf10 antibodies

PROTEIN BROWSER

C10orf10-001	C10orf10-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C10orf10-001 ENSP00000298295 ENST00000298295	Q9NTK1 [Direct mapping] Protein DEPP Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005739 [mitochondrion] Show all	212 aa 23.4 kDa	Yes	0
C10orf10-003 ENSP00000414494 ENST00000448778	X6RKE0 [Direct mapping] Protein DEPP Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		84 aa 9.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.