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Most of the cancer cells displayed weak to moderate cytoplasmic and nuclear positivity. Lymphomas along with several breast, prostate, cervical and endometrial cancers were negative.
Squamous cell carcinomas of head and neck cancers and papillary adenocarcinomas of thyroid showed strong membranous and cytoplasmic staining. Several cases of skin, urothelial and renal cancers displayed moderate to strong positivity. Several cases of gliomas, lymphomas, melanomas, liver and pancreatic cancers displayed moderate to strong cytoplasmic positivity. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
KBTBD6 (HGNC Symbol)
Synonyms
DKFZp547E1912
Description
Kelch repeat and BTB (POZ) domain containing 6 (HGNC Symbol)