Expression of FRMD7 in cancer - Summary

CANCER ATLAS

Gene description

FERM domain containing 7

Protein class

Cancer-related genes, Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA000886

GENE INFORMATION
Gene name	FRMD7 (HGNC Symbol)
Synonyms	FLJ43346, NYS, NYS1
Description	FERM domain containing 7 (HGNC Symbol)
Entrez gene summary	Mutations in this gene are associated with X-linked congenital nystagmus. [provided by RefSeq, Dec 2008]
Chromosome	X
Cytoband	q26.2
Chromosome location (bp)	132076993 - 132128020
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165694 (version 83.38)
Entrez gene	90167
UniProt	Q6ZUT3 (UniProt - Evidence at protein level)
neXtProt	NX_Q6ZUT3
Antibodypedia	FRMD7 antibodies

PROTEIN BROWSER

FRMD7-001	FRMD7-002	FRMD7-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FRMD7-001 ENSP00000359916 ENST00000370879	X6R7S7 [Direct mapping] FERM domain-containing protein 7; Uncharacterized protein Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Show all	GO:0005856 [cytoskeleton] Show all	594 aa 67.8 kDa	No	0
FRMD7-002 ENSP00000298542 ENST00000298542	Q6ZUT3 [Direct mapping] FERM domain-containing protein 7 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Disease related genes Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005856 [cytoskeleton] GO:0010592 [positive regulation of lamellipodium assembly] GO:0010975 [regulation of neuron projection development] GO:0030426 [growth cone] GO:0032091 [negative regulation of protein binding] GO:0043005 [neuron projection] GO:0043025 [neuronal cell body] GO:0051057 [positive regulation of small GTPase mediated signal transduction] GO:0051497 [negative regulation of stress fiber assembly] Show all	714 aa 81.6 kDa	No	0
FRMD7-003 ENSP00000417996 ENST00000464296	Q6ZUT3 [Direct mapping] FERM domain-containing protein 7 Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Disease related genes Show all	GO:0003674 [molecular_function] GO:0005615 [extracellular space] GO:0005856 [cytoskeleton] GO:0010975 [regulation of neuron projection development] GO:0030426 [growth cone] GO:0043005 [neuron projection] GO:0043025 [neuronal cell body] Show all	699 aa 79.8 kDa	No	0