Tissue expression of METTL17 - Summary - The Human Protein Atlas

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METTL17

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	METTL17
Gene description	Methyltransferase like 17
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA059802
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	METTL17 (HGNC Symbol)
Synonyms	FLJ20859, METT11D1
Description	Methyltransferase like 17 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	20989770 - 20997035
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165792 (version 83.38)
Entrez gene	64745
UniProt	Q9H7H0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H7H0
Antibodypedia	METTL17 antibodies

PROTEIN BROWSER

METTL17-001	METTL17-002	METTL17-005	METTL17-014	METTL17-015	METTL17-016	METTL17-019	METTL17-027

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
METTL17-001 ENSP00000343041 ENST00000339374	Q9H7H0 [Direct mapping] Methyltransferase-like protein 17, mitochondrial Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0005840 [ribosome] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0032259 [methylation] Show all	456 aa 50.7 kDa	Yes	0
METTL17-002 ENSP00000372445 ENST00000382985	Q9H7H0 [Direct mapping] Methyltransferase-like protein 17, mitochondrial Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0005840 [ribosome] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0032259 [methylation] Show all	478 aa 53.1 kDa	Yes	0
METTL17-005 ENSP00000450794 ENST00000556670	Q9H7H0 [Direct mapping] Methyltransferase-like protein 17, mitochondrial Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0005840 [ribosome] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0032259 [methylation] Show all	447 aa 49.6 kDa	Yes	0
METTL17-014 ENSP00000451478 ENST00000553564	G3V3X6 [Direct mapping] Methyltransferase-like protein 17, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] GO:0005654 [nucleoplasm] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0032259 [methylation] Show all	140 aa 16.1 kDa	No	0
METTL17-015 ENSP00000451913 ENST00000554751	G3V4P2 [Direct mapping] Methyltransferase-like protein 17, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] Show all	102 aa 11.9 kDa	No	0
METTL17-016 ENSP00000451804 ENST00000554283	G3V4H5 [Direct mapping] Methyltransferase-like protein 17, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] Show all	186 aa 20.9 kDa	No	0
METTL17-019 ENSP00000451049 ENST00000555670	G3V353 [Direct mapping] Methyltransferase-like protein 17, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] GO:0005654 [nucleoplasm] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0032259 [methylation] Show all	174 aa 19.8 kDa	No	0
METTL17-027 ENSP00000452238 ENST00000556733	H0YJW1 [Direct mapping] Methyltransferase-like protein 17, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0032259 [methylation] Show all	123 aa 13.7 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.