Cell atlas - ZNF219 - The Human Protein Atlas

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ZNF219

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF219
Gene description	Zinc finger protein 219
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA056168
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus.

Main location

Nucleus (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA056168	HeLa	Nucleoplasm
	HPA056168	Hep G2	Nucleus
	HPA056168	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	ZNF219
Synonyms
Description	Zinc finger protein 219 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	21090046 - 21104722
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165804 (version 83.38)
Entrez gene	51222
UniProt	Q9P2Y4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P2Y4
Antibodypedia	ZNF219 antibodies

PROTEIN BROWSER

ZNF219-001	ZNF219-002	ZNF219-003	ZNF219-005	ZNF219-006	ZNF219-007	ZNF219-009	ZNF219-010	ZNF219-011	ZNF219-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF219-001 ENSP00000354206 ENST00000360947	Q9P2Y4 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0001505 [regulation of neurotransmitter levels] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0004969 [histamine receptor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007275 [multicellular organismal development] GO:0016021 [integral component of membrane] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	722 aa 76.9 kDa	No	0
ZNF219-002 ENSP00000388558 ENST00000451119	Q9P2Y4 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0001505 [regulation of neurotransmitter levels] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0004969 [histamine receptor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007275 [multicellular organismal development] GO:0016021 [integral component of membrane] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	722 aa 76.9 kDa	No	0
ZNF219-003 ENSP00000392401 ENST00000421093	Q9P2Y4 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0001505 [regulation of neurotransmitter levels] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0004969 [histamine receptor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007275 [multicellular organismal development] GO:0016021 [integral component of membrane] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	722 aa 76.9 kDa	No	0
ZNF219-005 ENSP00000451595 ENST00000555697	G3V452 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		31 aa 3.4 kDa	No	0
ZNF219-006 ENSP00000451969 ENST00000553980	G3V4T1 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	57 aa 6.3 kDa	No	0
ZNF219-007 ENSP00000451212 ENST00000554478	G3V3F2 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	158 aa 17.1 kDa	No	0
ZNF219-009 ENSP00000450609 ENST00000556174	G3V2E3 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	111 aa 12.1 kDa	No	0
ZNF219-010 ENSP00000451890 ENST00000554923	G3V4M7 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	145 aa 15.6 kDa	No	0
ZNF219-011 ENSP00000450803 ENST00000555270	G3V2Q8 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	211 aa 23.2 kDa	No	0
ZNF219-013 ENSP00000450900 ENST00000553296	G3V2W3 [Direct mapping] Zinc finger protein 219 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	107 aa 11.6 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.