Tissue expression of SALL2 - Summary - The Human Protein Atlas

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SALL2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SALL2
Gene description	Spalt-like transcription factor 2
Protein class	Disease related genes Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (parathyroid gland)
GTEx:	Tissue enhanced (cerebellum)
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in several tissues.

DATA RELIABILITY
Data reliability description	External characterization data supports antibody staining.
Reliability score	Approved based on 1 antibody. HPA004162
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (parathyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebellum)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	SALL2 (HGNC Symbol)
Synonyms	Hsal2, KIAA0360, ZNF795
Description	Spalt-like transcription factor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	21521081 - 21537216
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165821 (version 83.38)
Entrez gene	6297
UniProt	Q9Y467 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y467
Antibodypedia	SALL2 antibodies

PROTEIN BROWSER

SALL2-001	SALL2-003	SALL2-004	SALL2-005	SALL2-006	SALL2-008	SALL2-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SALL2-001 ENSP00000483562 ENST00000614342	Q9Y467 [Direct mapping] Sal-like protein 2 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001654 [eye development] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0007165 [signal transduction] GO:0016581 [NuRD complex] GO:0021915 [neural tube development] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	1007 aa 105.4 kDa	No	0
SALL2-003 ENSP00000483202 ENST00000613414	A0A0B4J2F7 [Direct mapping] Sal-like protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		200 aa 21.3 kDa	No	0
SALL2-004 ENSP00000440054 ENST00000546363	H0YFS7 [Direct mapping] Sal-like protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	902 aa 94.9 kDa	No	0
SALL2-005 ENSP00000484460 ENST00000611430	A0A087X1T9 [Direct mapping] Sal-like protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		198 aa 20.9 kDa	No	0
SALL2-006 ENSP00000396773 ENST00000450879	E7EW59 [Direct mapping] Sal-like protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	906 aa 95.4 kDa	No	0
SALL2-008 ENSP00000438493 ENST00000537235	F5H433 [Direct mapping] Sal-like protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		191 aa 19.7 kDa	No	0
SALL2-009 ENSP00000439654 ENST00000541965	F5H1G6 [Direct mapping] Sal-like protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		99 aa 9.9 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.