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Most cancer cells showed weak to moderate cytoplasmic positivity. A few cases of endometrial and lung cancers were strongly stained. Gliomas, lymphomas and testicular cancers were mainly negative.
GENE INFORMATION
Gene name
TRUB1 (HGNC Symbol)
Synonyms
PUS4
Description
TruB pseudouridine (psi) synthase family member 1 (HGNC Symbol)
Entrez gene summary
Pseudouridine is an abundant component of rRNAs and tRNAs and is enzymatically generated by isomerization of uridine by pseudouridine synthase (Zucchini et al., 2003 [PubMed 12736709]).[supplied by OMIM, Mar 2008]
SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)