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Several cases of squamous cell carcinomas, malignant melanomas and renal cancers exhibited moderate to strong cytoplasmic/membranous immunoreactivity. Endothelial cells were distinctly stained. Remaining malignant cells were mainly negative.
GENE INFORMATION
Gene name
UBTD1 (HGNC Symbol)
Synonyms
FLJ11807
Description
Ubiquitin domain containing 1 (HGNC Symbol)
Entrez gene summary
The degradation of many proteins is carried out by the ubiquitin pathway in which proteins are targeted for degradation by covalent conjugation of the polypeptide ubiquitin. This gene encodes a protein that belongs to the ubiquitin family of proteins. The encoded protein is thought to regulate E2 ubiquitin conjugating enzymes belonging to the UBE2D family. [provided by RefSeq, Mar 2014]
