Expression of SMCO2 in cancer - Summary

CANCER ATLAS

Gene description

Single-pass membrane protein with coiled-coil domains 2

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA014366

GENE INFORMATION
Gene name	SMCO2 (HGNC Symbol)
Synonyms	C12orf70, LOC341346
Description	Single-pass membrane protein with coiled-coil domains 2 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	p11.23
Chromosome location (bp)	27466810 - 27502185
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165935 (version 83.38)
Entrez gene	341346
UniProt	A6NFE2 (UniProt - Evidence at transcript level)
neXtProt	NX_A6NFE2
Antibodypedia	SMCO2 antibodies

PROTEIN BROWSER

SMCO2-001	SMCO2-002	SMCO2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SMCO2-001 ENSP00000441688 ENST00000535986	A6NFE2 [Direct mapping] Single-pass membrane and coiled-coil domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	343 aa 39.5 kDa	No	1
SMCO2-002 ENSP00000298876 ENST00000298876	J3KNC3 [Direct mapping] Single-pass membrane and coiled-coil domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	293 aa 33.8 kDa	No	1
SMCO2-201 ENSP00000387617 ENST00000416383	A6NFE2 [Direct mapping] Single-pass membrane and coiled-coil domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	343 aa 39.5 kDa	No	1