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A majority of cancer tissues showed weak to moderate cytoplasmic positivity with additional membranous staining in a few cases. Gliomas and lymphomas were generally negative.
GENE INFORMATION
Gene name
ARL5B (HGNC Symbol)
Synonyms
ARL8
Description
ADP-ribosylation factor-like 5B (HGNC Symbol)
Entrez gene summary
ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.[supplied by OMIM, Nov 2010]
