Expression of LRTM2 in cancer - Summary

CANCER ATLAS

Gene description

Leucine-rich repeats and transmembrane domains 2

Protein class

Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA055094

GENE INFORMATION
Gene name	LRTM2
Synonyms
Description	Leucine-rich repeats and transmembrane domains 2 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	p13.33
Chromosome location (bp)	1820267 - 1836752
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166159 (version 83.38)
Entrez gene	654429
UniProt	Q8N967 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N967
Antibodypedia	LRTM2 antibodies

PROTEIN BROWSER

LRTM2-001	LRTM2-002	LRTM2-003	LRTM2-004	LRTM2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRTM2-001 ENSP00000299194 ENST00000299194	Q8N967 [Direct mapping] Leucine-rich repeat and transmembrane domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0007409 [axonogenesis] GO:0016021 [integral component of membrane] Show all	370 aa 41.2 kDa	Yes	1
LRTM2-002 ENSP00000444737 ENST00000535041	Q8N967 [Direct mapping] Leucine-rich repeat and transmembrane domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0007409 [axonogenesis] GO:0016021 [integral component of membrane] Show all	370 aa 41.2 kDa	Yes	1
LRTM2-003 ENSP00000438678 ENST00000546167	F5H2B4 [Direct mapping] Leucine-rich repeat and transmembrane domain-containing protein 2 Show all	SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		93 aa 10 kDa	Yes	0
LRTM2-004 ENSP00000444104 ENST00000543694	F5GZY9 [Direct mapping] Leucine-rich repeat and transmembrane domain-containing protein 2 Show all	SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		96 aa 10.4 kDa	Yes	0
LRTM2-201 ENSP00000446278 ENST00000543818	Q8N967 [Direct mapping] Leucine-rich repeat and transmembrane domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0007409 [axonogenesis] GO:0016021 [integral component of membrane] GO:0051965 [positive regulation of synapse assembly] Show all	370 aa 41.2 kDa	Yes	1