Expression of PRTG in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Protogenin

Protein class

Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA032138

GENE INFORMATION
Gene name	PRTG (HGNC Symbol)
Synonyms	FLJ25756, IGDCC5
Description	Protogenin (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the immunoglobulin superfamily. The encoded transmembrane protein has been associated with the development of various tissues, especially neurogenesis. It has been suggested that this gene may be associated with attention deficit hyperactivity disorder (ADHD). [provided by RefSeq, Nov 2014]
Chromosome	15
Cytoband	q21.3
Chromosome location (bp)	55611546 - 55743090
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166450 (version 83.38)
Entrez gene	283659
UniProt	Q2VWP7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q2VWP7
Antibodypedia	PRTG antibodies

PROTEIN BROWSER

PRTG-001	PRTG-002	PRTG-004	PRTG-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRTG-001 ENSP00000373937 ENST00000389286	Q2VWP7 [Direct mapping] Protogenin Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0007275 [multicellular organismal development] GO:0016021 [integral component of membrane] Show all	1150 aa 127.1 kDa	Yes	1
PRTG-002 ENSP00000453160 ENST00000561465	H0YLD1 [Direct mapping] Protogenin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	218 aa 24.6 kDa	No	0
PRTG-004 ENSP00000453335 ENST00000561292	H0YLT7 [Direct mapping] Protogenin; Protogenin homolog (Gallus gallus), isoform CRA_b Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	137 aa 15.2 kDa	Yes	0
PRTG-005 ENSP00000452760 ENST00000558349	H0YKD6 [Direct mapping] Protogenin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		22 aa 2.5 kDa	No	0