Distinct cytoplasmic and membranous positivity was observed in cases of urothelial carcinomas as well as squamous cell carcinomas in lung and cervix. A majority of testicular cancers showed moderate immunoreactivity. Remaining malignant cells were in general weakly stained or negative.
CLEC4D (HGNC Symbol)
CD368, CLECSF8, Mpcl
C-type lectin domain family 4, member D (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]