Cell atlas - GALR1 - The Human Protein Atlas

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GALR1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GALR1
Gene description	Galanin receptor 1
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GALR1 (HGNC Symbol)
Synonyms	GALNR, GALNR1
Description	Galanin receptor 1 (HGNC Symbol)
Entrez gene summary	The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]
Chromosome	18
Cytoband	q23
Chromosome location (bp)	77250549 - 77277896
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166573 (version 83.38)
Entrez gene	2587
UniProt	P47211 (UniProt - Evidence at protein level)
neXtProt	NX_P47211
Antibodypedia	GALR1 antibodies

PROTEIN BROWSER

GALR1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GALR1-001 ENSP00000299727 ENST00000299727	P47211 [Direct mapping] Galanin receptor type 1 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004966 [galanin receptor activity] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway] GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007586 [digestion] GO:0016021 [integral component of membrane] GO:0017046 [peptide hormone binding] GO:0042923 [neuropeptide binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0051464 [positive regulation of cortisol secretion] Show all	349 aa 39 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.