Tissue expression of SERPINB12 - Summary

GENERAL INFORMATION
Gene name	SERPINB12
Gene description	Serpin peptidase inhibitor, clade B (ovalbumin), member 12
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (skin)
GTEx:	Group enriched (skin, vagina, cervix, uterine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (skin)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (skin, vagina, cervix, uterine)

GENE INFORMATION
Gene name	SERPINB12 (HGNC Symbol)
Synonyms	YUKOPIN
Description	Serpin peptidase inhibitor, clade B (ovalbumin), member 12 (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband	q21.33
Chromosome location (bp)	63556160 - 63567011
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166634 (version 83.38)
Entrez gene	89777
UniProt	Q96P63 (UniProt - Evidence at protein level)
neXtProt	NX_Q96P63
Antibodypedia	SERPINB12 antibodies

PROTEIN BROWSER

SERPINB12-001	SERPINB12-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SERPINB12-001 ENSP00000269491 ENST00000269491	Q96P63 [Direct mapping] Serpin B12 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004867 [serine-type endopeptidase inhibitor activity] GO:0005615 [extracellular space] GO:0005737 [cytoplasm] GO:0010951 [negative regulation of endopeptidase activity] GO:0019899 [enzyme binding] GO:0042177 [negative regulation of protein catabolic process] GO:0070062 [extracellular exosome] Show all	405 aa 46.3 kDa	No	0
SERPINB12-002 ENSP00000372218 ENST00000382768	Q96P63 [Direct mapping] Serpin B12 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002244 [hematopoietic progenitor cell differentiation] GO:0004867 [serine-type endopeptidase inhibitor activity] GO:0005615 [extracellular space] GO:0005737 [cytoplasm] GO:0010951 [negative regulation of endopeptidase activity] GO:0019899 [enzyme binding] GO:0042177 [negative regulation of protein catabolic process] GO:0070062 [extracellular exosome] Show all	425 aa 48.4 kDa	No	0