Cell atlas - ZNF592 - The Human Protein Atlas

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ZNF592

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF592
Gene description	Zinc finger protein 592
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA021600
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA021600	A-431	Nucleoplasm
	HPA021600	U-2 OS	Nucleoplasm
	HPA021600	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	ZNF592 (HGNC Symbol)
Synonyms	CAMOS, KIAA0211, SCAR5
Description	Zinc finger protein 592 (HGNC Symbol)
Entrez gene summary	This gene is thought to play a role in a complex developmental pathway and the regulation of genes involved in cerebellar development. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia. [provided by RefSeq, Jan 2011]
Chromosome	15
Cytoband	q25.3
Chromosome location (bp)	84748635 - 84806432
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166716 (version 83.38)
Entrez gene	9640
UniProt	Q92610 (UniProt - Evidence at protein level)
neXtProt	NX_Q92610
Antibodypedia	ZNF592 antibodies

PROTEIN BROWSER

ZNF592-001	ZNF592-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF592-001 ENSP00000452877 ENST00000560079	Q92610 [Direct mapping] Zinc finger protein 592 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	1267 aa 137.5 kDa	No	0
ZNF592-201 ENSP00000299927 ENST00000299927	Q92610 [Direct mapping] Zinc finger protein 592 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	1267 aa 137.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.