Cell atlas - VPS39 - The Human Protein Atlas

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VPS39

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	VPS39
Gene description	Vacuolar protein sorting 39 homolog (S. cerevisiae)
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	VPS39 (HGNC Symbol)
Synonyms	KIAA0770, VAM6
Description	Vacuolar protein sorting 39 homolog (S. cerevisiae) (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Chromosome	15
Cytoband	q15.1
Chromosome location (bp)	42158701 - 42208316
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166887 (version 83.38)
Entrez gene	23339
UniProt	Q96JC1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96JC1
Antibodypedia	VPS39 antibodies

PROTEIN BROWSER

VPS39-001	VPS39-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
VPS39-001 ENSP00000326534 ENST00000318006	Q96JC1 [Direct mapping] Vam6/Vps39-like protein A0A024R9L9 [Target identity:100%; Query identity:100%] Vacuolar protein sorting 39 (Yeast), isoform CRA_b Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005765 [lysosomal membrane] GO:0006886 [intracellular protein transport] GO:0006914 [autophagy] GO:0008333 [endosome to lysosome transport] GO:0016192 [vesicle-mediated transport] GO:0030897 [HOPS complex] GO:0031902 [late endosome membrane] GO:0034058 [endosomal vesicle fusion] GO:1902774 [late endosome to lysosome transport] GO:1990126 [retrograde transport, endosome to plasma membrane] Show all	875 aa 100.8 kDa	No	0
VPS39-002 ENSP00000335193 ENST00000348544	Q96JC1 [Direct mapping] Vam6/Vps39-like protein Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005765 [lysosomal membrane] GO:0006886 [intracellular protein transport] GO:0006914 [autophagy] GO:0008333 [endosome to lysosome transport] GO:0016192 [vesicle-mediated transport] GO:0030123 [AP-3 adaptor complex] GO:0030897 [HOPS complex] GO:0031902 [late endosome membrane] GO:0034058 [endosomal vesicle fusion] GO:1902774 [late endosome to lysosome transport] GO:1990126 [retrograde transport, endosome to plasma membrane] Show all	886 aa 101.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.