Expression of TSC22D4 in cancer - Summary

CANCER ATLAS

Gene description

TSC22 domain family, member 4

Protein class

Predicted intracellular proteins, Predicted secreted proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Melanoma

STAINING SUMMARY

HPA006757

GENE INFORMATION
Gene name	TSC22D4 (HGNC Symbol)
Synonyms	THG-1, TILZ2
Description	TSC22 domain family, member 4 (HGNC Symbol)
Entrez gene summary	TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3; MIM 300506) (Kester et al., 1999 [PubMed 10488076]; Fiorenza et al., 2001 [PubMed 11707329]).[supplied by OMIM, Mar 2008]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	100463359 - 100479279
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166925 (version 83.38)
Entrez gene	81628
UniProt	Q9Y3Q8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y3Q8
Antibodypedia	TSC22D4 antibodies

PROTEIN BROWSER

TSC22D4-001	TSC22D4-002	TSC22D4-005	TSC22D4-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TSC22D4-001 ENSP00000300181 ENST00000300181	Q9Y3Q8 [Direct mapping] TSC22 domain family protein 4 Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006970 [response to osmotic stress] GO:0045892 [negative regulation of transcription, DNA-templated] Show all	395 aa 41 kDa	No	0
TSC22D4-002 ENSP00000377560 ENST00000393991	Q9Y3Q8 [Direct mapping] TSC22 domain family protein 4 Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0045892 [negative regulation of transcription, DNA-templated] Show all	156 aa 16.7 kDa	No	0
TSC22D4-005 ENSP00000395795 ENST00000456330	H7C0M8 [Direct mapping] TSC22 domain family protein 4 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		168 aa 17.1 kDa	Yes	0
TSC22D4-006 ENSP00000388168 ENST00000423266	H7BZ77 [Direct mapping] TSC22 domain family protein 4 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	211 aa 21.7 kDa	Yes	0