Expression of MBD6 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Methyl-CpG binding domain protein 6

Protein class

Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Melanoma

STAINING SUMMARY

HPA038948	HPA038949

GENE INFORMATION
Gene name	MBD6 (HGNC Symbol)
Synonyms	KIAA1887
Description	Methyl-CpG binding domain protein 6 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q13.3
Chromosome location (bp)	57520710 - 57530148
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166987 (version 83.38)
Entrez gene	114785
UniProt	Q96DN6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96DN6
Antibodypedia	MBD6 antibodies

PROTEIN BROWSER

MBD6-001	MBD6-005	MBD6-006	MBD6-008	MBD6-009	MBD6-010	MBD6-011	MBD6-013	MBD6-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MBD6-001 ENSP00000347896 ENST00000355673	Q96DN6 [Direct mapping] Methyl-CpG-binding domain protein 6 A0A024RBA3 [Target identity:100%; Query identity:100%] Methyl-CpG binding domain protein 6, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0010369 [chromocenter] Show all	1003 aa 101.2 kDa	No	0
MBD6-005 ENSP00000448070 ENST00000548887	F8VU14 [Direct mapping] Methyl-CpG-binding domain protein 6 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	148 aa 15.4 kDa	No	0
MBD6-006 ENSP00000450370 ENST00000551351	F8VNX1 [Direct mapping] Methyl-CpG-binding domain protein 6 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	53 aa 5.5 kDa	No	0
MBD6-008 ENSP00000449603 ENST00000546805	F8VVK7 [Direct mapping] Methyl-CpG-binding domain protein 6 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	73 aa 7.6 kDa	No	0
MBD6-009 ENSP00000448202 ENST00000546632	F8VNX1 [Direct mapping] Methyl-CpG-binding domain protein 6 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	53 aa 5.5 kDa	No	0
MBD6-010 ENSP00000446481 ENST00000549623	F8VPC4 [Direct mapping] Methyl-CpG-binding domain protein 6 Show all	Predicted intracellular proteins Show all		66 aa 6.9 kDa	No	0
MBD6-011 ENSP00000447365 ENST00000552255	F8VZD7 [Direct mapping] Methyl-CpG-binding domain protein 6 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	45 aa 4.5 kDa	No	0
MBD6-013 ENSP00000446834 ENST00000552659	H0YHD1 [Direct mapping] Methyl-CpG-binding domain protein 6 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	177 aa 18 kDa	No	0
MBD6-015 ENSP00000450160 ENST00000552163	H0YIU1 [Direct mapping] Methyl-CpG-binding domain protein 6 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		190 aa 19.9 kDa	Yes	0