Cell atlas - B4GALNT2 - The Human Protein Atlas

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B4GALNT2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	B4GALNT2
Gene description	Beta-1,4-N-acetyl-galactosaminyl transferase 2
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	B4GALNT2 (HGNC Symbol)
Synonyms	Cad, GALGT2, Sda
Description	Beta-1,4-N-acetyl-galactosaminyl transferase 2 (HGNC Symbol)
Entrez gene summary	B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an alpha-2,3-linked sialic acid. B4GALNT2 also catalyzes the last step in the biosynthesis of the Cad antigen (Montiel et al., 2003 [PubMed 12678917]).[supplied by OMIM, Mar 2008]
Chromosome	17
Cytoband	q21.32
Chromosome location (bp)	49132460 - 49176840
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167080 (version 83.38)
Entrez gene	124872
UniProt	Q8NHY0 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NHY0
Antibodypedia	B4GALNT2 antibodies

PROTEIN BROWSER

B4GALNT2-001	B4GALNT2-002	B4GALNT2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
B4GALNT2-001 ENSP00000300404 ENST00000300404	Q8NHY0 [Direct mapping] Beta-1,4 N-acetylgalactosaminyltransferase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006047 [UDP-N-acetylglucosamine metabolic process] GO:0006486 [protein glycosylation] GO:0008376 [acetylgalactosaminyltransferase activity] GO:0016021 [integral component of membrane] GO:0016758 [transferase activity, transferring hexosyl groups] GO:0019276 [UDP-N-acetylgalactosamine metabolic process] GO:0022408 [negative regulation of cell-cell adhesion] GO:0030173 [integral component of Golgi membrane] GO:0030259 [lipid glycosylation] Show all	566 aa 63.3 kDa	No	1
B4GALNT2-002 ENSP00000377022 ENST00000393354	Q8NHY0 [Direct mapping] Beta-1,4 N-acetylgalactosaminyltransferase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006486 [protein glycosylation] GO:0008376 [acetylgalactosaminyltransferase activity] GO:0016021 [integral component of membrane] GO:0016758 [transferase activity, transferring hexosyl groups] GO:0019276 [UDP-N-acetylgalactosamine metabolic process] GO:0022408 [negative regulation of cell-cell adhesion] GO:0030173 [integral component of Golgi membrane] GO:0030259 [lipid glycosylation] Show all	506 aa 57 kDa	No	1
B4GALNT2-003 ENSP00000425510 ENST00000504681	Q8NHY0 [Direct mapping] Beta-1,4 N-acetylgalactosaminyltransferase 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006486 [protein glycosylation] GO:0008376 [acetylgalactosaminyltransferase activity] GO:0016021 [integral component of membrane] GO:0019276 [UDP-N-acetylgalactosamine metabolic process] GO:0022408 [negative regulation of cell-cell adhesion] GO:0030173 [integral component of Golgi membrane] GO:0030259 [lipid glycosylation] Show all	480 aa 54.2 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.