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TBC1D21

GENERAL INFORMATION

Gene name

 TBC1D21

Gene description

 TBC1 domain family, member 21

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA043319
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 TBC1D21 (HGNC Symbol)

Synonyms

 MGC34741, MgcRabGAP

Description

 TBC1 domain family, member 21 (HGNC Symbol)

Entrez gene summary

Chromosome

 15

Cytoband

 q24.1

Chromosome location (bp)

 73873608 - 73889214

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167139 (version 83.38)

Entrez gene

 161514

UniProt

 Q8IYX1 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8IYX1

Antibodypedia

 TBC1D21 antibodies

PROTEIN BROWSER
TBC1D21-001
TBC1D21-002
TBC1D21-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TBC1D21-001
ENSP00000300504
ENST00000300504
Q8IYX1 [Direct mapping]
TBC1 domain family member 21
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0001669 [acrosomal vesicle]
GO:0003779 [actin binding]
GO:0005096 [GTPase activator activity]
GO:0043547 [positive regulation of GTPase activity]
GO:0070062 [extracellular exosome]
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 336 aa
39.2 kDa 		No 0
TBC1D21-002
ENSP00000439325
ENST00000535547
Q8IYX1 [Direct mapping]
TBC1 domain family member 21
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Predicted intracellular proteins
Show all
GO:0005096 [GTPase activator activity]
GO:0043547 [positive regulation of GTPase activity]
GO:0070062 [extracellular exosome]
Show all
 300 aa
35 kDa 		No 0
TBC1D21-003
ENSP00000457096
ENST00000562056
H3BTA9 [Direct mapping]
TBC1 domain family member 21
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Predicted intracellular proteins
Show all
 299 aa
35 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.