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KATNAL2

GENERAL INFORMATION

Gene name

 KATNAL2

Gene description

 Katanin p60 subunit A-like 2

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (parathyroid gland)
GTEx:Mixed
FANTOM5:Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous nuclear and nuclear membrane expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA040712 , HPA042029
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (parathyroid gland)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION

Gene name

 KATNAL2 (HGNC Symbol)

Synonyms

 DKFZP667C165, MGC33211

Description

 Katanin p60 subunit A-like 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 18

Cytoband

 q21.1

Chromosome location (bp)

 46917492 - 47102243

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167216 (version 83.38)

Entrez gene

 83473

UniProt

 Q8IYT4 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8IYT4

Antibodypedia

 KATNAL2 antibodies

PROTEIN BROWSER
KATNAL2-001
KATNAL2-002
KATNAL2-006
KATNAL2-007
KATNAL2-008
KATNAL2-009
KATNAL2-010

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KATNAL2-001
ENSP00000245121
ENST00000245121
Q8IYT4 [Direct mapping]
Katanin p60 ATPase-containing subunit A-like 2
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Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0008568 [microtubule-severing ATPase activity]
GO:0031122 [cytoplasmic microtubule organization]
GO:0051013 [microtubule severing]
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 466 aa
52.8 kDa 		No 0
KATNAL2-002
ENSP00000467488
ENST00000591522
K7EPQ6 [Direct mapping]
Katanin p60 ATPase-containing subunit A-like 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008568 [microtubule-severing ATPase activity]
GO:0031122 [cytoplasmic microtubule organization]
Show all
 154 aa
16.9 kDa 		No 0
KATNAL2-006
ENSP00000464779
ENST00000588433
K7EIJ8 [Direct mapping]
Katanin p60 ATPase-containing subunit A-like 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008568 [microtubule-severing ATPase activity]
GO:0031122 [cytoplasmic microtubule organization]
Show all
 341 aa
38 kDa 		No 0
KATNAL2-007
ENSP00000466302
ENST00000586198
K7EM02 [Direct mapping]
Katanin p60 ATPase-containing subunit A-like 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008568 [microtubule-severing ATPase activity]
GO:0031122 [cytoplasmic microtubule organization]
Show all
 128 aa
14 kDa 		No 0
KATNAL2-008
ENSP00000467610
ENST00000592005
K7EQ00 [Direct mapping]
Katanin p60 ATPase-containing subunit A-like 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008568 [microtubule-severing ATPase activity]
GO:0031122 [cytoplasmic microtubule organization]
Show all
 105 aa
11.8 kDa 		No 0
KATNAL2-009
ENSP00000466674
ENST00000585469
K7EMW1 [Direct mapping]
Katanin p60 ATPase-containing subunit A-like 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0008568 [microtubule-severing ATPase activity]
GO:0031122 [cytoplasmic microtubule organization]
Show all
 222 aa
25.5 kDa 		No 0
KATNAL2-010
ENSP00000348478
ENST00000356157
Q8IYT4 [Direct mapping]
Katanin p60 ATPase-containing subunit A-like 2
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0008568 [microtubule-severing ATPase activity]
GO:0031122 [cytoplasmic microtubule organization]
GO:0051013 [microtubule severing]
Show all
 538 aa
61.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.