Expression of FN3K in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Fructosamine 3 kinase

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA061358

GENE INFORMATION
Gene name	FN3K
Synonyms
Description	Fructosamine 3 kinase (HGNC Symbol)
Entrez gene summary	A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012]
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	82735575 - 82751197
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167363 (version 83.38)
Entrez gene	64122
UniProt	Q9H479 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H479
Antibodypedia	FN3K antibodies

PROTEIN BROWSER

FN3K-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FN3K-001 ENSP00000300784 ENST00000300784	Q9H479 [Direct mapping] Fructosamine-3-kinase Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005575 [cellular_component] GO:0016310 [phosphorylation] GO:0030387 [fructosamine-3-kinase activity] GO:0030389 [fructosamine metabolic process] GO:0030393 [fructoselysine metabolic process] GO:0030855 [epithelial cell differentiation] Show all	309 aa 35.2 kDa	No	0