Expression of TMC4 in cancer - Summary - The Human Protein Atlas

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TMC4

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Transmembrane channel-like 4

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA048635

GENE INFORMATION
Gene name	TMC4
Synonyms
Description	Transmembrane channel-like 4 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.42
Chromosome location (bp)	54160108 - 54173250
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167608 (version 83.38)
Entrez gene	147798
UniProt
neXtProt
Antibodypedia	TMC4 antibodies

PROTEIN BROWSER

TMC4-001	TMC4-002	TMC4-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMC4-001 ENSP00000479458 ENST00000619895	A0A087WVI4 [Direct mapping] Transmembrane channel-like protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	706 aa 78.7 kDa	No	9
TMC4-002 ENSP00000416444 ENST00000446291	C9JFU4 [Direct mapping] Transmembrane channel-like protein 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	176 aa 19.7 kDa	No	2
TMC4-011 ENSP00000477627 ENST00000617472	A0A087WT65 [Direct mapping] Transmembrane channel-like protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	712 aa 79.3 kDa	No	9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.