Expression of TMIGD2 in cancer - Summary

CANCER ATLAS

Gene description

Transmembrane and immunoglobulin domain containing 2

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA011081

GENE INFORMATION
Gene name	TMIGD2 (HGNC Symbol)
Synonyms	CD28H, IGPR-1, MGC23244
Description	Transmembrane and immunoglobulin domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	4292232 - 4302431
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167664 (version 83.38)
Entrez gene	126259
UniProt	Q96BF3 (UniProt - Evidence at protein level)
neXtProt	NX_Q96BF3
Antibodypedia	TMIGD2 antibodies

PROTEIN BROWSER

TMIGD2-001	TMIGD2-002	TMIGD2-003	TMIGD2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMIGD2-001 ENSP00000301272 ENST00000301272	Q96BF3 [Direct mapping] Transmembrane and immunoglobulin domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0001819 [positive regulation of cytokine production] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0015026 [coreceptor activity] GO:0016021 [integral component of membrane] GO:0031295 [T cell costimulation] GO:0042104 [positive regulation of activated T cell proliferation] GO:0045766 [positive regulation of angiogenesis] Show all	282 aa 30.7 kDa	Yes	1
TMIGD2-002 ENSP00000470561 ENST00000595645	Q96BF3 [Direct mapping] Transmembrane and immunoglobulin domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0001819 [positive regulation of cytokine production] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0015026 [coreceptor activity] GO:0016021 [integral component of membrane] GO:0031295 [T cell costimulation] GO:0042104 [positive regulation of activated T cell proliferation] GO:0045766 [positive regulation of angiogenesis] Show all	278 aa 30.3 kDa	Yes	1
TMIGD2-003 ENSP00000470494 ENST00000600114	A0A0B4J2A9 [Direct mapping] Transmembrane and immunoglobulin domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	162 aa 17.7 kDa	No	1
TMIGD2-004 ENSP00000471821 ENST00000600349	A0A0B4J2B0 [Direct mapping] Transmembrane and immunoglobulin domain-containing protein 2 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		110 aa 12 kDa	No	0