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TBX10

CANCER ATLAS

Gene description

 T-box 10

Protein class

 Predicted secreted proteins, Transcription factors

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA047881

GENE INFORMATION

Gene name

 TBX10 (HGNC Symbol)

Synonyms

 TBX13, TBX7

Description

 T-box 10 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate. [provided by RefSeq, Nov 2010]

Chromosome

 11

Cytoband

 q13.2

Chromosome location (bp)

 67631303 - 67639560

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167800 (version 83.38)

Entrez gene

 347853

UniProt

 O75333 (UniProt - Evidence at transcript level)

neXtProt

 NX_O75333

Antibodypedia

 TBX10 antibodies

PROTEIN BROWSER
TBX10-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TBX10-001
ENSP00000335191
ENST00000335385
O75333 [Direct mapping]
T-box transcription factor TBX10
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Transcription factors
   Immunoglobulin fold
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
Show all
 385 aa
42.3 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.