Tissue expression of MGAT5B - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	MGAT5B
Gene description	Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (cerebral cortex)
GTEx:	Tissue enhanced (cerebral cortex, caudate)
FANTOM5:	Tissue enhanced (caudate, brain, hippocampus)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebral cortex, caudate)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (caudate, brain, hippocampus)

GENE INFORMATION
Gene name	MGAT5B (HGNC Symbol)
Synonyms	FLJ25132, GnT-IX, GnT-VB
Description	Mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (HGNC Symbol)
Entrez gene summary	The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]
Chromosome	17
Cytoband	q25.2
Chromosome location (bp)	76868456 - 76950393
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167889 (version 83.38)
Entrez gene	146664
UniProt	Q3V5L5 (UniProt - Evidence at protein level)
neXtProt	NX_Q3V5L5
Antibodypedia	MGAT5B antibodies

PROTEIN BROWSER

MGAT5B-001	MGAT5B-002	MGAT5B-003	MGAT5B-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MGAT5B-001 ENSP00000301618 ENST00000301618	Q3V5L5 [Direct mapping] Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B Show all	Enzymes ENZYME proteins Transferases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0016021 [integral component of membrane] GO:0030144 [alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity] GO:0046872 [metal ion binding] Show all	790 aa 89.3 kDa	No	0
MGAT5B-002 ENSP00000391227 ENST00000428789	Q3V5L5 [Direct mapping] Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005794 [Golgi apparatus] GO:0006487 [protein N-linked glycosylation] GO:0016021 [integral component of membrane] GO:0030144 [alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity] GO:0046872 [metal ion binding] Show all	801 aa 90.6 kDa	No	1
MGAT5B-003 ENSP00000457614 ENST00000565675	H3BR20 [Direct mapping] Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0006487 [protein N-linked glycosylation] GO:0016021 [integral component of membrane] GO:0030144 [alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity] Show all	110 aa 12.3 kDa	No	0
MGAT5B-010 ENSP00000456037 ENST00000569840	Q3V5L5 [Direct mapping] Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B Show all	Enzymes ENZYME proteins Transferases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0016021 [integral component of membrane] GO:0030144 [alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity] GO:0046872 [metal ion binding] Show all	792 aa 89.5 kDa	No	0