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GSDMA

GENERAL INFORMATION

Gene name

 GSDMA

Gene description

 Gasdermin A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (skin)
GTEx:Tissue enriched (skin)
FANTOM5:Group enriched (tonsil, epididymis, lymph node)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in sebaceous glands and epidermal cells of skin.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA023313 , HPA064826
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skin)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skin)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (tonsil, epididymis, lymph node)

GENE INFORMATION

Gene name

 GSDMA (HGNC Symbol)

Synonyms

 FLJ39120, GSDM, GSDM1

Description

 Gasdermin A (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q21.1

Chromosome location (bp)

 39962973 - 39977766

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167914 (version 83.38)

Entrez gene

 284110

UniProt

 Q96QA5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96QA5

Antibodypedia

 GSDMA antibodies

PROTEIN BROWSER
GSDMA-001
GSDMA-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GSDMA-001
ENSP00000301659
ENST00000301659
Q96QA5 [Direct mapping]
Gasdermin-A
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0006915 [apoptotic process]
GO:0048471 [perinuclear region of cytoplasm]
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 445 aa
49.4 kDa 		No 0
GSDMA-002
ENSP00000461985
ENST00000577447
J3KRG2 [Direct mapping]
Gasdermin-A
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 159 aa
17.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.