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Moderate to strong cytoplasmic positivity was observed in most malignancies. Gliomas, lymphomas, testicular and renal cancer were negative or weakly stained.
GENE INFORMATION
Gene name
KRT24 (HGNC Symbol)
Synonyms
FLJ20261, MGC138169, MGC138173
Description
Keratin 24, type I (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jun 2009]
