Fields »
ABOUT
HELP
BLOG
RAB26

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 RAB26

Gene description

 RAB26, member RAS oncogene family

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the plasma membrane & vesicles. In addition localized to the centrosome.

RNA cell category

 Cell line enhanced (SCLC-21H, SK-BR-3, A549, HeLa)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Vesicles (uncertain), Plasma membrane (uncertain)

Additional location

 In addition localized to the Centrosome (uncertain)

Single-cell variation

 Single-cell variation in protein expression observed.

DATA RELIABILITY

Reliability score

 Uncertain based on 1 antibody.
HPA075624
SHOW MORE

ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, SK-BR-3, A549, HeLa)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the plasma membrane & vesicles. In addition localized to the centrosome.

Main location

 Vesicles (uncertain), Plasma membrane (uncertain)

Additional location

 Centrosome (uncertain)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA075624 HeLa Vesicles Intensity
Plasma membrane
HPA075624 MCF7 Cell Junctions
Centrosome
Cytosol
HPA075624 U-2 OS Plasma membrane
Centrosome

GENE INFORMATION

Gene name

 RAB26

Synonyms

Description

 RAB26, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

 Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010]

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 2140803 - 2154165

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167964 (version 83.38)

Entrez gene

 25837

UniProt

 Q9ULW5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9ULW5

Antibodypedia

 RAB26 antibodies

PROTEIN BROWSER
RAB26-001
RAB26-004
RAB26-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB26-001
ENSP00000210187
ENST00000210187
Q9ULW5 [Direct mapping]
Ras-related protein Rab-26
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0009306 [protein secretion]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0017157 [regulation of exocytosis]
GO:0019002 [GMP binding]
GO:0030658 [transport vesicle membrane]
GO:0030667 [secretory granule membrane]
GO:0031226 [intrinsic component of plasma membrane]
GO:0032482 [Rab protein signal transduction]
GO:0035272 [exocrine system development]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0045055 [regulated secretory pathway]
Show all
 256 aa
27.9 kDa 		Yes 0
RAB26-004
ENSP00000441580
ENST00000541451
Q9ULW5 [Direct mapping]
Ras-related protein Rab-26
Show all
Predicted intracellular proteins
Show all
GO:0000139 [Golgi membrane]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0009306 [protein secretion]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0017157 [regulation of exocytosis]
GO:0019002 [GMP binding]
GO:0030658 [transport vesicle membrane]
GO:0030667 [secretory granule membrane]
GO:0031226 [intrinsic component of plasma membrane]
GO:0032482 [Rab protein signal transduction]
GO:0035272 [exocrine system development]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0045055 [regulated secretory pathway]
Show all
 190 aa
21.4 kDa 		No 0
RAB26-008
ENSP00000455675
ENST00000566724
H3BQ97 [Direct mapping]
Ras-related protein Rab-26
Show all
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0009306 [protein secretion]
GO:0017157 [regulation of exocytosis]
GO:0030667 [secretory granule membrane]
GO:0032482 [Rab protein signal transduction]
Show all
 136 aa
13.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.