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MLST8

CANCER ATLAS

Gene description

 MTOR associated protein, LST8 homolog

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA041841
CAB019935

GENE INFORMATION

Gene name

 MLST8 (HGNC Symbol)

Synonyms

 GbetaL, GBL, Lst8, Pop3

Description

 MTOR associated protein, LST8 homolog (HGNC Symbol)

Entrez gene summary

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 2204248 - 2209416

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167965 (version 83.38)

Entrez gene

 64223

UniProt

 Q9BVC4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BVC4

Antibodypedia

 MLST8 antibodies

PROTEIN BROWSER
MLST8-001
MLST8-002
MLST8-003
MLST8-004
MLST8-008
MLST8-012
MLST8-016
MLST8-018
MLST8-020
MLST8-023

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MLST8-001
ENSP00000456405
ENST00000569417
Q9BVC4 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0007050 [cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016236 [macroautophagy]
GO:0030838 [positive regulation of actin filament polymerization]
GO:0031295 [T cell costimulation]
GO:0032008 [positive regulation of TOR signaling]
GO:0032956 [regulation of actin cytoskeleton organization]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0043087 [regulation of GTPase activity]
GO:0045087 [innate immune response]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048015 [phosphatidylinositol-mediated signaling]
GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation]
GO:1900034 [regulation of cellular response to heat]
Show all
 326 aa
35.9 kDa 		No 0
MLST8-002
ENSP00000301724
ENST00000301724
A0A0A0MR05 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 327 aa
36 kDa 		No 0
MLST8-003
ENSP00000380313
ENST00000397124
Q9BVC4 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0007050 [cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016236 [macroautophagy]
GO:0031295 [T cell costimulation]
GO:0032008 [positive regulation of TOR signaling]
GO:0032956 [regulation of actin cytoskeleton organization]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0045087 [innate immune response]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048015 [phosphatidylinositol-mediated signaling]
GO:1900034 [regulation of cellular response to heat]
Show all
 326 aa
35.9 kDa 		No 0
MLST8-004
ENSP00000457870
ENST00000564088
Q9BVC4 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0007050 [cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016236 [macroautophagy]
GO:0031295 [T cell costimulation]
GO:0032008 [positive regulation of TOR signaling]
GO:0032956 [regulation of actin cytoskeleton organization]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0045087 [innate immune response]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048015 [phosphatidylinositol-mediated signaling]
GO:1900034 [regulation of cellular response to heat]
Show all
 326 aa
35.9 kDa 		No 0
MLST8-008
ENSP00000371888
ENST00000382450
Q9BVC4 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0007050 [cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016236 [macroautophagy]
GO:0031295 [T cell costimulation]
GO:0032008 [positive regulation of TOR signaling]
GO:0032956 [regulation of actin cytoskeleton organization]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0045087 [innate immune response]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048015 [phosphatidylinositol-mediated signaling]
GO:1900034 [regulation of cellular response to heat]
Show all
 325 aa
35.7 kDa 		No 0
MLST8-012
ENSP00000455046
ENST00000565250
Q9BVC4 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0007050 [cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016236 [macroautophagy]
GO:0031295 [T cell costimulation]
GO:0032008 [positive regulation of TOR signaling]
GO:0032956 [regulation of actin cytoskeleton organization]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0045087 [innate immune response]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048015 [phosphatidylinositol-mediated signaling]
GO:1900034 [regulation of cellular response to heat]
Show all
 326 aa
35.9 kDa 		No 0
MLST8-016
ENSP00000455642
ENST00000563179
H3BQ74 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 51 aa
5.5 kDa 		No 0
MLST8-018
ENSP00000454698
ENST00000569457
H3BN58 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 202 aa
22.3 kDa 		No 0
MLST8-020
ENSP00000456944
ENST00000562352
H3BSZ4 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 275 aa
30.2 kDa 		No 0
MLST8-023
ENSP00000456046
ENST00000562479
H3BR25 [Direct mapping]
Target of rapamycin complex subunit LST8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 166 aa
18.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.