Cell atlas - CCDC88B - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CCDC88B

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Cytosol
	Nucleoplasm

Human cell
	Centrosome
	Cytosol
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	CCDC88B
Gene description	Coiled-coil domain containing 88B
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the centrosome. In addition localized to the cytosol & nucleoplasm.
RNA cell category	Cell line enhanced (HMC-1)
Protein evidence	Evidence at protein level
Main location	Localized to the Centrosome (approved)
Additional location	In addition localized to the Nucleoplasm (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA026652
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HMC-1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the centrosome. In addition localized to the cytosol & nucleoplasm.

Main location

Centrosome (approved)

Additional location

Nucleoplasm (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA026652	HeLa	Nucleoplasm
	HPA026652	HeLa	Centrosome
	HPA026652	U-2 OS	Nucleoplasm
			Centrosome
			Cytosol
	HPA026652	U-251 MG	Nucleoplasm
			Centrosome
			Cytosol

GENE INFORMATION
Gene name	CCDC88B (HGNC Symbol)
Synonyms	BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3
Description	Coiled-coil domain containing 88B (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules. [provided by RefSeq, Oct 2009]
Chromosome	11
Cytoband	q13.1
Chromosome location (bp)	64340223 - 64357534
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168071 (version 83.38)
Entrez gene	283234
UniProt	A6NC98 (UniProt - Evidence at protein level)
neXtProt	NX_A6NC98
Antibodypedia	CCDC88B antibodies

PROTEIN BROWSER

CCDC88B-001	CCDC88B-005	CCDC88B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC88B-001 ENSP00000349238 ENST00000356786	A6NC98 [Direct mapping] Coiled-coil domain-containing protein 88B Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] Show all	1476 aa 164.8 kDa	Yes	0
CCDC88B-005 ENSP00000352974 ENST00000359902	H7BY33 [Direct mapping] Coiled-coil domain-containing protein 88B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		712 aa 80.7 kDa	No	0
CCDC88B-201 ENSP00000301897 ENST00000301897	A6NC98 [Direct mapping] Coiled-coil domain-containing protein 88B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] Show all	139 aa 15.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.