Cell atlas - PTGDR - The Human Protein Atlas

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PTGDR

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	PTGDR
Gene description	Prostaglandin D2 receptor (DP)
Protein class	Disease related genes G-protein coupled receptors Potential drug targets Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	PTGDR (HGNC Symbol)
Synonyms	DP, DP1, PTGDR1
Description	Prostaglandin D2 receptor (DP) (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Chromosome	14
Cytoband	q22.1
Chromosome location (bp)	52267713 - 52276724
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000168229 (version 83.38)
Entrez gene	5729
UniProt	Q13258 (UniProt - Evidence at transcript level)
neXtProt	NX_Q13258
Antibodypedia	PTGDR antibodies

PROTEIN BROWSER

PTGDR-001	PTGDR-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PTGDR-001 ENSP00000303424 ENST00000306051	Q13258 [Direct mapping] Prostaglandin D2 receptor Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0001785 [prostaglandin J receptor activity] GO:0004930 [G-protein coupled receptor activity] GO:0004956 [prostaglandin D receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0006954 [inflammatory response] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0030238 [male sex determination] GO:0030431 [sleep] GO:0046085 [adenosine metabolic process] GO:0071799 [cellular response to prostaglandin D stimulus] Show all	359 aa 40.3 kDa	No	7
PTGDR-002 ENSP00000452408 ENST00000553372	Q13258 [Direct mapping] Prostaglandin D2 receptor Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004956 [prostaglandin D receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	296 aa 32.4 kDa	No	6

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.