Cell atlas - FAM107A - The Human Protein Atlas

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FAM107A

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear speckles

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	FAM107A
Gene description	Family with sequence similarity 107, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nuclear speckles.
RNA cell category	Cell line enriched (HUVEC TERT2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear speckles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA055888
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (HUVEC TERT2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nuclear speckles.

Main location

Nuclear speckles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA055888	HUVEC TERT2	Nuclear speckles
	HPA055888	U-2 OS	Nuclear speckles
	HPA055888	U-251 MG	Nuclear speckles

GENE INFORMATION
Gene name	FAM107A (HGNC Symbol)
Synonyms	DRR1, TU3A
Description	Family with sequence similarity 107, member A (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband
Chromosome location (bp)	58564117 - 58627610
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168309 (version 83.38)
Entrez gene	11170
UniProt	O95990 (UniProt - Evidence at protein level)
neXtProt	NX_O95990
Antibodypedia	FAM107A antibodies

PROTEIN BROWSER

FAM107A-001	FAM107A-002	FAM107A-003	FAM107A-004	FAM107A-005	FAM107A-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM107A-001 ENSP00000419124 ENST00000474531	O95990 [Direct mapping] Protein FAM107A A0A024R327 [Target identity:100%; Query identity:100%] Family with sequence similarity 107, member A, isoform CRA_c Show all	Predicted intracellular proteins Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	175 aa 20.9 kDa	No	0
FAM107A-002 ENSP00000354270 ENST00000360997	O95990 [Direct mapping] Protein FAM107A Q6IAM1 [Target identity:100%; Query identity:100%] Family with sequence similarity 107 member A transcript variant; Family with sequence similarity 107, member A, isoform CRA_a; TU3A protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	144 aa 17.5 kDa	No	0
FAM107A-003 ENSP00000400858 ENST00000447756	O95990 [Direct mapping] Protein FAM107A Show all	Predicted intracellular proteins Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	172 aa 20.5 kDa	No	0
FAM107A-004 ENSP00000377991 ENST00000394481	O95990 [Direct mapping] Protein FAM107A Q6IAM1 [Target identity:100%; Query identity:100%] Family with sequence similarity 107 member A transcript variant; Family with sequence similarity 107, member A, isoform CRA_a; TU3A protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	144 aa 17.5 kDa	No	0
FAM107A-005 ENSP00000419529 ENST00000464064	O95990 [Direct mapping] Protein FAM107A Show all	Predicted intracellular proteins Show all	GO:0001558 [regulation of cell growth] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	135 aa 15.9 kDa	No	0
FAM107A-007 ENSP00000418038 ENST00000465970	C9JAU5 [Direct mapping] Protein FAM107A Show all	Predicted intracellular proteins Show all		105 aa 12.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.