Cell atlas - ARF4 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ARF4

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ARF4
Gene description	ADP-ribosylation factor 4
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ARF4 (HGNC Symbol)
Synonyms	ARF2
Description	ADP-ribosylation factor 4 (HGNC Symbol)
Entrez gene summary	This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	p14.3
Chromosome location (bp)	57571363 - 57598220
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168374 (version 83.38)
Entrez gene	378
UniProt	P18085 (UniProt - Evidence at protein level)
neXtProt	NX_P18085
Antibodypedia	ARF4 antibodies

PROTEIN BROWSER

ARF4-001	ARF4-003	ARF4-004	ARF4-006	ARF4-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARF4-001 ENSP00000306010 ENST00000303436	P18085 [Direct mapping] ADP-ribosylation factor 4 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005154 [epidermal growth factor receptor binding] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006471 [protein ADP-ribosylation] GO:0006886 [intracellular protein transport] GO:0006996 [organelle organization] GO:0007173 [epidermal growth factor receptor signaling pathway] GO:0007264 [small GTPase mediated signal transduction] GO:0007420 [brain development] GO:0007612 [learning] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016192 [vesicle-mediated transport] GO:0016477 [cell migration] GO:0031584 [activation of phospholipase D activity] GO:0032587 [ruffle membrane] GO:0043066 [negative regulation of apoptotic process] GO:0043197 [dendritic spine] GO:0045176 [apical protein localization] GO:0045197 [establishment or maintenance of epithelial cell apical/basal polarity] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048678 [response to axon injury] GO:0060996 [dendritic spine development] GO:0061512 [protein localization to cilium] GO:0070062 [extracellular exosome] GO:2000377 [regulation of reactive oxygen species metabolic process] Show all	180 aa 20.5 kDa	No	0
ARF4-003 ENSP00000475828 ENST00000489843	U3KQF2 [Direct mapping] ADP-ribosylation factor 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	71 aa 8 kDa	No	0
ARF4-004 ENSP00000417501 ENST00000496292	C9JAK5 [Direct mapping] ADP-ribosylation factor 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0006886 [intracellular protein transport] GO:0007264 [small GTPase mediated signal transduction] Show all	153 aa 17.7 kDa	No	0
ARF4-006 ENSP00000420254 ENST00000463880	C9JPM4 [Direct mapping] ADP-ribosylation factor 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] Show all	127 aa 14.6 kDa	No	0
ARF4-009 ENSP00000418388 ENST00000488156	C9J6P1 [Direct mapping] ADP-ribosylation factor 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		22 aa 2.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.