Expression of MFSD2A in cancer - Summary

CANCER ATLAS

Gene description

Major facilitator superfamily domain containing 2A

Protein class

Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA043107

GENE INFORMATION
Gene name	MFSD2A (HGNC Symbol)
Synonyms	FLJ14490, MFSD2
Description	Major facilitator superfamily domain containing 2A (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.2
Chromosome location (bp)	39955112 - 39969968
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168389 (version 83.38)
Entrez gene	84879
UniProt	Q8NA29 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NA29
Antibodypedia	MFSD2A antibodies

PROTEIN BROWSER

MFSD2A-001	MFSD2A-002	MFSD2A-004	MFSD2A-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MFSD2A-001 ENSP00000361898 ENST00000372811	Q8NA29 [Direct mapping] Sodium-dependent lysophosphatidylcholine symporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014) Show all	GO:0005548 [phospholipid transporter activity] GO:0005737 [cytoplasm] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0015293 [symporter activity] GO:0015908 [fatty acid transport] GO:0045056 [transcytosis] GO:0055085 [transmembrane transport] GO:0060856 [establishment of blood-brain barrier] GO:1990379 [lipid transport across blood brain barrier] Show all	530 aa 58.6 kDa	No	>9
MFSD2A-002 ENSP00000361895 ENST00000372809	Q8NA29 [Direct mapping] Sodium-dependent lysophosphatidylcholine symporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014) Show all	GO:0005548 [phospholipid transporter activity] GO:0005737 [cytoplasm] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0015293 [symporter activity] GO:0015908 [fatty acid transport] GO:0015914 [phospholipid transport] GO:0045056 [transcytosis] GO:0055085 [transmembrane transport] GO:0060856 [establishment of blood-brain barrier] GO:1990379 [lipid transport across blood brain barrier] Show all	543 aa 60.2 kDa	No	>9
MFSD2A-004 ENSP00000407606 ENST00000434861	Q5SSK0 [Direct mapping] Sodium-dependent lysophosphatidylcholine symporter 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] Show all	266 aa 29.1 kDa	No	7
MFSD2A-201 ENSP00000391261 ENST00000420632	E7EPI8 [Direct mapping] Sodium-dependent lysophosphatidylcholine symporter 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] Show all	374 aa 41.4 kDa	No	7