Cell atlas - PHYHIP - The Human Protein Atlas

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PHYHIP

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	PHYHIP
Gene description	Phytanoyl-CoA 2-hydroxylase interacting protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the mitochondria.
RNA cell category	Cell line enhanced (RPMI-8226)
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (supported)

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA068030 , HPA069318
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RPMI-8226) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the mitochondria.

Main location

Mitochondria (supported)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA068030	SK-MEL-30	Mitochondria
HPA068030	U-2 OS	Mitochondria
HPA069318	SH-SY5Y	Mitochondria
HPA069318	SK-MEL-30	Nucleus
HPA069318	SK-MEL-30	Mitochondria
HPA069318	U-2 OS	Mitochondria

GENE INFORMATION
Gene name	PHYHIP (HGNC Symbol)
Synonyms	DYRK1AP3, KIAA0273, PAHX-AP
Description	Phytanoyl-CoA 2-hydroxylase interacting protein (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	p21.3
Chromosome location (bp)	22219704 - 22232341
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168490 (version 83.38)
Entrez gene	9796
UniProt	Q92561 (UniProt - Evidence at protein level)
neXtProt	NX_Q92561
Antibodypedia	PHYHIP antibodies

PROTEIN BROWSER

PHYHIP-001	PHYHIP-002	PHYHIP-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PHYHIP-001 ENSP00000415491 ENST00000454243	Q92561 [Direct mapping] Phytanoyl-CoA hydroxylase-interacting protein Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002230 [positive regulation of defense response to virus by host] GO:0005515 [protein binding] GO:0098779 [mitophagy in response to mitochondrial depolarization] Show all	330 aa 37.6 kDa	No	0
PHYHIP-002 ENSP00000320017 ENST00000321613	Q92561 [Direct mapping] Phytanoyl-CoA hydroxylase-interacting protein Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002230 [positive regulation of defense response to virus by host] GO:0005515 [protein binding] GO:0098779 [mitophagy in response to mitochondrial depolarization] Show all	330 aa 37.6 kDa	No	0
PHYHIP-005 ENSP00000430870 ENST00000523252	E5RHN5 [Direct mapping] Phytanoyl-CoA hydroxylase-interacting protein Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		248 aa 28.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.