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MYL1

GENERAL INFORMATION

Gene name

 MYL1

Gene description

 Myosin, light chain 1, alkali; skeletal, fast

Protein class

 Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (skeletal muscle)
GTEx:Tissue enriched (skeletal muscle)
FANTOM5:Tissue enriched (skeletal muscle)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in skeletal muscle.

DATA RELIABILITY

Data reliability
description

 Pending external verification. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 2 antibodies.
HPA046859 , HPA063034
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)

GENE INFORMATION

Gene name

 MYL1

Synonyms

Description

 Myosin, light chain 1, alkali; skeletal, fast (HGNC Symbol)

Entrez gene summary

 Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q34

Chromosome location (bp)

 210290150 - 210315190

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000168530 (version 83.38)

Entrez gene

 4632

UniProt

 P05976 (UniProt - Evidence at transcript level)

neXtProt

 NX_P05976

Antibodypedia

 MYL1 antibodies

PROTEIN BROWSER
MYL1-001
MYL1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MYL1-001
ENSP00000307280
ENST00000352451
P05976 [Direct mapping]
Myosin light chain 1/3, skeletal muscle isoform
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005829 [cytosol]
GO:0005859 [muscle myosin complex]
GO:0006936 [muscle contraction]
GO:0008307 [structural constituent of muscle]
GO:0030016 [myofibril]
GO:0030017 [sarcomere]
GO:0030049 [muscle filament sliding]
GO:0043292 [contractile fiber]
GO:0060048 [cardiac muscle contraction]
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 194 aa
21.1 kDa 		Yes 0
MYL1-002
ENSP00000343321
ENST00000341685
P05976 [Direct mapping]
Myosin light chain 1/3, skeletal muscle isoform
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005829 [cytosol]
GO:0005859 [muscle myosin complex]
GO:0006936 [muscle contraction]
GO:0008307 [structural constituent of muscle]
GO:0030016 [myofibril]
GO:0030017 [sarcomere]
GO:0030049 [muscle filament sliding]
Show all
 150 aa
16.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.