Cell atlas - NSG1 - The Human Protein Atlas

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NSG1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	NSG1
Gene description	Neuron specific gene family member 1
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the mitochondria.
RNA cell category	Group enriched (SCLC-21H, TIME, SH-SY5Y, SK-MEL-30, U-698)
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA035775
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (SCLC-21H, TIME, SH-SY5Y, SK-MEL-30, U-698) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the mitochondria.

Main location

Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA035775	SK-MEL-30	Mitochondria
	HPA035775	U-2 OS	Mitochondria
	HPA035775	U-251 MG	Mitochondria

GENE INFORMATION
Gene name	NSG1
Synonyms
Description	Neuron specific gene family member 1 (EntrezGene)
Entrez gene summary
Chromosome	4
Cytoband	p16.3
Chromosome location (bp)	4348140 - 4419058
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168824 (version 83.38)
Entrez gene	27065
UniProt	P42857 (UniProt - Evidence at protein level)
neXtProt	NX_P42857
Antibodypedia	NSG1 antibodies

PROTEIN BROWSER

NSG1-001	NSG1-002	NSG1-003	NSG1-004	NSG1-008	NSG1-009	NSG1-201	NSG1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NSG1-001 ENSP00000388823 ENST00000421177	P42857 [Target identity:100%; Query identity:100%] Neuron-specific protein family member 1 B2R5R8 [Target identity:100%; Query identity:100%] DNA segment on chromosome 4 (Unique) 234 expressed sequence, isoform CRA_b; cDNA FLJ37254 fis, clone BRAMY2008583, highly similar to Neuron-specific protein family member 1; cDNA FLJ43182 fis, clone FCBBF3018453, highly similar to Neuron-specific protein family member 1; cDNA, FLJ92590, Homo sapiens DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), mRNA Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0001921 [positive regulation of receptor recycling] GO:0005102 [receptor binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005768 [endosome] GO:0007212 [dopamine receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0016197 [endosomal transport] GO:0016328 [lateral plasma membrane] GO:0032051 [clathrin light chain binding] GO:0045211 [postsynaptic membrane] GO:0048268 [clathrin coat assembly] Show all	185 aa 20.9 kDa	No	1
NSG1-002 ENSP00000426358 ENST00000513555	P42857 [Target identity:100%; Query identity:100%] Neuron-specific protein family member 1 B2R5R8 [Target identity:100%; Query identity:100%] DNA segment on chromosome 4 (Unique) 234 expressed sequence, isoform CRA_b; cDNA FLJ37254 fis, clone BRAMY2008583, highly similar to Neuron-specific protein family member 1; cDNA FLJ43182 fis, clone FCBBF3018453, highly similar to Neuron-specific protein family member 1; cDNA, FLJ92590, Homo sapiens DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), mRNA Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007212 [dopamine receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0032051 [clathrin light chain binding] GO:0048268 [clathrin coat assembly] Show all	185 aa 20.9 kDa	No	1
NSG1-003 ENSP00000408833 ENST00000433139	P42857 [Target identity:100%; Query identity:100%] Neuron-specific protein family member 1 B2R5R8 [Target identity:100%; Query identity:100%] DNA segment on chromosome 4 (Unique) 234 expressed sequence, isoform CRA_b; cDNA FLJ37254 fis, clone BRAMY2008583, highly similar to Neuron-specific protein family member 1; cDNA FLJ43182 fis, clone FCBBF3018453, highly similar to Neuron-specific protein family member 1; cDNA, FLJ92590, Homo sapiens DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), mRNA Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007212 [dopamine receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0032051 [clathrin light chain binding] GO:0048268 [clathrin coat assembly] Show all	185 aa 20.9 kDa	No	1
NSG1-004 ENSP00000425803 ENST00000504171	A0A0A6YYJ2 [Direct mapping] Neuron-specific protein family member 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0007212 [dopamine receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0032051 [clathrin light chain binding] GO:0048268 [clathrin coat assembly] Show all	146 aa 16.5 kDa	No	1
NSG1-008 ENSP00000421841 ENST00000505246	P42857 [Target identity:100%; Query identity:100%] Neuron-specific protein family member 1 B2R5R8 [Target identity:100%; Query identity:100%] DNA segment on chromosome 4 (Unique) 234 expressed sequence, isoform CRA_b; cDNA FLJ37254 fis, clone BRAMY2008583, highly similar to Neuron-specific protein family member 1; cDNA FLJ43182 fis, clone FCBBF3018453, highly similar to Neuron-specific protein family member 1; cDNA, FLJ92590, Homo sapiens DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), mRNA Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007212 [dopamine receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0032051 [clathrin light chain binding] GO:0048268 [clathrin coat assembly] Show all	185 aa 20.9 kDa	No	1
NSG1-009 ENSP00000425423 ENST00000506380	P42857 [Target identity:100%; Query identity:100%] Neuron-specific protein family member 1 B2R5R8 [Target identity:100%; Query identity:100%] DNA segment on chromosome 4 (Unique) 234 expressed sequence, isoform CRA_b; cDNA FLJ37254 fis, clone BRAMY2008583, highly similar to Neuron-specific protein family member 1; cDNA FLJ43182 fis, clone FCBBF3018453, highly similar to Neuron-specific protein family member 1; cDNA, FLJ92590, Homo sapiens DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), mRNA Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007212 [dopamine receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0032051 [clathrin light chain binding] GO:0048268 [clathrin coat assembly] Show all	185 aa 20.9 kDa	No	1
NSG1-201 ENSP00000381049 ENST00000397958	P42857 [Target identity:100%; Query identity:100%] Neuron-specific protein family member 1 B2R5R8 [Target identity:100%; Query identity:100%] DNA segment on chromosome 4 (Unique) 234 expressed sequence, isoform CRA_b; cDNA FLJ37254 fis, clone BRAMY2008583, highly similar to Neuron-specific protein family member 1; cDNA FLJ43182 fis, clone FCBBF3018453, highly similar to Neuron-specific protein family member 1; cDNA, FLJ92590, Homo sapiens DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), mRNA Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007212 [dopamine receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0032051 [clathrin light chain binding] GO:0048268 [clathrin coat assembly] Show all	185 aa 20.9 kDa	No	1
NSG1-202 ENSP00000480081 ENST00000621129	P42857 [Target identity:100%; Query identity:100%] Neuron-specific protein family member 1 B2R5R8 [Target identity:100%; Query identity:100%] DNA segment on chromosome 4 (Unique) 234 expressed sequence, isoform CRA_b; cDNA FLJ37254 fis, clone BRAMY2008583, highly similar to Neuron-specific protein family member 1; cDNA FLJ43182 fis, clone FCBBF3018453, highly similar to Neuron-specific protein family member 1; cDNA, FLJ92590, Homo sapiens DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), mRNA Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007212 [dopamine receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0032051 [clathrin light chain binding] GO:0048268 [clathrin coat assembly] Show all	185 aa 20.9 kDa	No	1

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.