Expression of HTR1E in cancer - Summary

CANCER ATLAS

Gene description

5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled

Protein class

G-protein coupled receptors, Plasma proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA004931

GENE INFORMATION
Gene name	HTR1E (HGNC Symbol)
Synonyms	5-HT1E
Description	5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q14.3
Chromosome location (bp)	86937306 - 87016683
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168830 (version 83.38)
Entrez gene	3354
UniProt	P28566 (UniProt - Evidence at protein level)
neXtProt	NX_P28566
Antibodypedia	HTR1E antibodies

PROTEIN BROWSER

HTR1E-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HTR1E-002 ENSP00000307766 ENST00000305344	P28566 [Direct mapping] 5-hydroxytryptamine receptor 1E Show all	G-protein coupled receptors GPCRs excl olfactory receptors Serotonin receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Plasma proteins Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004993 [serotonin receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007210 [serotonin receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0016021 [integral component of membrane] GO:0030815 [negative regulation of cAMP metabolic process] GO:0051378 [serotonin binding] Show all	365 aa 41.7 kDa	No	7