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STXBP6

CANCER ATLAS

Gene description

 Syntaxin binding protein 6 (amisyn)

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA003552

GENE INFORMATION

Gene name

 STXBP6 (HGNC Symbol)

Synonyms

 amisyn, HSPC156

Description

 Syntaxin binding protein 6 (amisyn) (HGNC Symbol)

Entrez gene summary

 STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).[supplied by OMIM, Mar 2008]

Chromosome

 14

Cytoband

 q12

Chromosome location (bp)

 24809656 - 25050297

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000168952 (version 83.38)

Entrez gene

 29091

UniProt

 Q8NFX7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NFX7

Antibodypedia

 STXBP6 antibodies

PROTEIN BROWSER
STXBP6-001
STXBP6-002
STXBP6-003
STXBP6-005
STXBP6-006
STXBP6-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STXBP6-001
ENSP00000379928
ENST00000396700
Q8NFX7 [Direct mapping]
Syntaxin-binding protein 6
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005886 [plasma membrane]
GO:0006887 [exocytosis]
GO:0006893 [Golgi to plasma membrane transport]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0017049 [GTP-Rho binding]
GO:0035542 [regulation of SNARE complex assembly]
GO:0045920 [negative regulation of exocytosis]
GO:0051601 [exocyst localization]
Show all
 210 aa
23.6 kDa 		No 0
STXBP6-002
ENSP00000397212
ENST00000419632
Q8NFX7 [Direct mapping]
Syntaxin-binding protein 6
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005886 [plasma membrane]
GO:0006887 [exocytosis]
GO:0006893 [Golgi to plasma membrane transport]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0017049 [GTP-Rho binding]
GO:0035542 [regulation of SNARE complex assembly]
GO:0045920 [negative regulation of exocytosis]
GO:0051601 [exocyst localization]
Show all
 210 aa
23.6 kDa 		No 0
STXBP6-003
ENSP00000449536
ENST00000546511
Q8NFX7 [Direct mapping]
Syntaxin-binding protein 6
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005886 [plasma membrane]
GO:0006887 [exocytosis]
GO:0006893 [Golgi to plasma membrane transport]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0017049 [GTP-Rho binding]
GO:0035542 [regulation of SNARE complex assembly]
GO:0045920 [negative regulation of exocytosis]
GO:0051601 [exocyst localization]
Show all
 210 aa
23.6 kDa 		No 0
STXBP6-005
ENSP00000447655
ENST00000548369
Q8NFX7 [Direct mapping]
Syntaxin-binding protein 6
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005886 [plasma membrane]
GO:0006887 [exocytosis]
GO:0006893 [Golgi to plasma membrane transport]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0017049 [GTP-Rho binding]
GO:0035542 [regulation of SNARE complex assembly]
GO:0045920 [negative regulation of exocytosis]
GO:0051601 [exocyst localization]
Show all
 108 aa
11.6 kDa 		No 0
STXBP6-006
ENSP00000324302
ENST00000323944
Q8NFX7 [Direct mapping]
Syntaxin-binding protein 6
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005886 [plasma membrane]
GO:0006887 [exocytosis]
GO:0006893 [Golgi to plasma membrane transport]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0017049 [GTP-Rho binding]
GO:0035542 [regulation of SNARE complex assembly]
GO:0045920 [negative regulation of exocytosis]
GO:0051601 [exocyst localization]
Show all
 210 aa
23.6 kDa 		No 0
STXBP6-007
ENSP00000449379
ENST00000550887
Q8NFX7 [Direct mapping]
Syntaxin-binding protein 6
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005886 [plasma membrane]
GO:0006887 [exocytosis]
GO:0006893 [Golgi to plasma membrane transport]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0017049 [GTP-Rho binding]
GO:0035542 [regulation of SNARE complex assembly]
GO:0045920 [negative regulation of exocytosis]
GO:0051601 [exocyst localization]
Show all
 210 aa
23.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.